HitPredict

Interactor 1: SERA (O43175)
D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399) (Malate dehydrogenase) (EC 1.1.1.37)
Gene: PHGDH

Interactor 2: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	31527615, unassigned1953, 25604459
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 533 Hs			1 595
+	Hs
		209428 SERA_HUMAN (1-533): 0: 667: 100.00		GCR_HUMAN (5-557): 4.69e-109: 346: 22.51
+	Hs
		209480 SERA_HUMAN (1-533): 0: 667: 100.00		NR4A1_HUMAN (64-549): 2.82e-105: 331: 24.54
+	Hs
		395775 CTBP2_HUMAN (21-383): 9.9e-118: 356: 29.10		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		396045 CTBP1_HUMAN (21-384): 1.27e-117: 355: 29.89		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		209448 SERA_HUMAN (1-533): 0: 667: 100.00		ANDR_HUMAN (172-455): 8.99e-37: 148: 30.16
+	Hs
		941509 CTBP2_HUMAN (21-383): 9.9e-118: 356: 29.10		ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88
+	Hs
		1103297 CTBP1_HUMAN (21-384): 1.27e-117: 355: 29.89		ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88
+	Mm
		312871 CTBP1_MOUSE (1-384): 4.13e-119: 359: 28.89		ERR2_MOUSE (92-547): 7.01e-113: 345: 34.42
+	Hs
		519886 CTBP2_HUMAN (21-383): 9.9e-118: 356: 29.10		ANDR_HUMAN (172-455): 8.99e-37: 148: 30.16
+	Hs
		520013 CTBP1_HUMAN (21-384): 1.27e-117: 355: 29.89		ANDR_HUMAN (172-455): 8.99e-37: 148: 30.16