HitPredict

Interactor 1: PRC1 (O43663)
Protein regulator of cytokinesis 1
Gene: PRC1

Interactor 2: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 620 Hs			1 1164
+	Hs
		209977 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33
+	Hs
		210172 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		MY18A_HUMAN (461-1064): 4e-25: 115: 10.31
+	Hs
		209715 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40
+	Hs
		148169 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		209640 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54
+	Hs
		210056 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		CYTSB_HUMAN (740-1117): 1.86e-12: 74.1: 12.41
+	Hs
		209903 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		CENPE_HUMAN (620-984): 9.03e-10: 65.5: 20.36
+	Hs
		209716 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		MYH10_HUMAN (687-992): 3.26e-09: 63.6: 20.43
+	Hs
		1268126 MRCKB_HUMAN (34-618): 1.68e-99: 335: 11.09		MY18A_HUMAN (461-1064): 4e-25: 115: 10.31
+	Hs
		1137871 MRCKA_HUMAN (34-613): 8.82e-106: 352: 13.04		MRCKA_HUMAN (278-842): 4.78e-17: 89.1: 8.78
+	Hs
		1137917 MRCKA_HUMAN (34-613): 8.82e-106: 352: 13.04		MRCKB_HUMAN (835-1162): 1.41e-15: 84.5: 6.67
+	Rn
		222472 MRCKA_RAT (34-613): 2.81e-107: 357: 13.21		MRCKA_RAT (415-804): 5.64e-14: 79.1: 8.05
+	Rn
		222476 MRCKA_RAT (34-613): 2.81e-107: 357: 13.21		MRCKB_RAT (856-1164): 4.53e-12: 72.9: 10.10
+	Rn
		1186812 MRCKB_RAT (34-618): 9.82e-104: 346: 11.74		MRCKB_RAT (856-1164): 4.53e-12: 72.9: 10.10
+	Hs
		1268060 MY18A_HUMAN (32-595): 2.83e-62: 226: 12.79		MY18A_HUMAN (461-1064): 4e-25: 115: 10.31
+	Hs
		724943 MY18A_HUMAN (32-595): 2.83e-62: 226: 12.79		MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40
+	Hs
		149126 MY18A_HUMAN (32-595): 2.83e-62: 226: 12.79		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		1129119 MY18A_HUMAN (32-595): 2.83e-62: 226: 12.79		CYTSB_HUMAN (740-1117): 1.86e-12: 74.1: 12.41