HitPredict

Interactor 1: SUMO2 (P61956)
Small ubiquitin-related modifier 2 (SUMO-2) (HSMT3) (SMT3 homolog 2) (SUMO-3) (Sentrin-2) (Ubiquitin-like protein SMT3B) (Smt3B)
Gene: SUMO2

Interactor 2: SMC3 (Q9UQE7)
Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3) (Basement membrane-associated chondroitin proteoglycan) (Bamacan) (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP)
Gene: SMC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	32786267
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 95 Hs			1 1217
+	Hs
		902772 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		SMC4_HUMAN (1-1206): 4.2e-80: 290: 16.85
+	Hs
		902586 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		SMC1A_HUMAN (2-1211): 5.21e-79: 286: 16.36
+	Hs
		311521 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		SMC2_HUMAN (1-1217): 1.65e-73: 269: 19.14
+	Ce
		823187 SUMO_CAEEL (1-93): 1.11e-33: 113: 46.24		DPY27_CAEEL (1-1203): 2.58e-75: 276: 14.49
+	At
		878967 SUMO1_ARATH (1-91): 8.61e-36: 118: 47.25		SMC1_ARATH (2-1204): 1.07e-70: 261: 16.80
+	Sc
		1015401 SMT3_YEAST (3-94): 4.25e-31: 106: 42.39		SMC4_YEAST (1-1207): 1.61e-67: 252: 17.37
+	Sc
		700812 SMT3_YEAST (3-94): 4.25e-31: 106: 42.39		SMC1_YEAST (2-1204): 3.58e-67: 250: 17.32