HitPredict

Interactor 1: TCF21 (O43680)
Transcription factor 21 (TCF-21) (Capsulin) (Class A basic helix-loop-helix protein 23) (bHLHa23) (Epicardin) (Podocyte-expressed 1) (Pod-1)
Gene: TCF21

Interactor 2: LMO4 (P61968)
LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4)
Gene: LMO4

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	15231748
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	HLH~LIM
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005667 - transcription regulator complex GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 179 Hs			1 165
+	Mm
		603898 TAL1_MOUSE (42-177): 3.04e-30: 114: 31.94		RBTN2_MOUSE (23-148): 3.99e-46: 149: 45.67
+	Hs
		546094 MYOG_HUMAN (6-179): 1.3e-33: 120: 18.08		LMO3_HUMAN (13-152): 4.29e-41: 136: 47.86
+	Mm
		604035 TAL1_MOUSE (42-177): 3.04e-30: 114: 31.94		LMO3_MOUSE (13-152): 4.29e-41: 136: 47.86
+	Mm
		1143746 TAL2_MOUSE (80-179): 7.4e-26: 96.9: 31.37		LMO3_MOUSE (13-152): 4.29e-41: 136: 47.86
+	Hs
		638508 TAL2_HUMAN (80-166): 8.49e-27: 99.6: 31.03		RBTN1_HUMAN (1-143): 1.92e-36: 125: 48.25
+	Hs
		568180 TAL1_HUMAN (38-177): 7.82e-25: 99: 26.17		RBTN1_HUMAN (1-143): 1.92e-36: 125: 48.25
+	Hs
		638295 TAL2_HUMAN (80-166): 8.49e-27: 99.6: 31.03		RBTN2_HUMAN (23-140): 7.68e-36: 123: 46.61
+	Hs
		568179 TAL1_HUMAN (38-177): 7.82e-25: 99: 26.17		RBTN2_HUMAN (23-140): 7.68e-36: 123: 46.61
+	Mm
		1143747 TAL2_MOUSE (80-179): 7.4e-26: 96.9: 31.37		RBTN1_MOUSE (1-152): 3.72e-36: 124: 47.37
+	Hs
		638265 HEN1_HUMAN (81-136): 8.71e-23: 89.9: 46.43		RBTN2_HUMAN (23-140): 7.68e-36: 123: 46.61
+	Dm
		1359764 Q9VHG3_DROME (12-154): 1.51e-27: 105: 21.80		Q9V472_DROME (87-165): 1.78e-12: 65.8: 15.39
+	Dm
		80870 DIMM_DROME (19-173): 1.19e-25: 103: 19.36		APTE_DROME (87-165): 1.67e-11: 63.1: 21.74
+	Dm
		114761 Q9VHG3_DROME (12-154): 1.51e-27: 105: 21.80		M9PD53_DROME (12-79): 1.17e-10: 60.8: 18.84
+	Hs
		551558 TFE2_HUMAN (4-175): 4.45e-26: 105: 16.38		LMX1A_HUMAN (15-82): 3.12e-10: 59.3: 30.44
+	Dm
		1368265 Q9W4I4_DROME (81-137): 3.66e-23: 91.8: 43.86		Q9VJ00_DROME (12-79): 1.65e-10: 60: 18.84
+	Dm
		112565 Q9W4I4_DROME (81-137): 3.66e-23: 91.8: 43.86		M9NCY1_DROME (12-79): 3.82e-10: 59.3: 18.84