HitPredict

Interactor 1: BUB1 (O43683)
Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A)
Gene: BUB1

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	38803224
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Pkinase~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1085 Hs			1 685
+	Hs
		236874 BUB1B_HUMAN (2-1078): 1.02e-166: 521: 19.02		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475723 KCC2D_HUMAN (774-1085): 1.18e-103: 336: 14.29		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		262227 ULK1_HUMAN (782-1002): 2.27e-14: 80.2: 18.55		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		182074 PDPK1_HUMAN (785-1032): 6.42e-14: 77.9: 18.50		UBC_HUMAN (1-685): 0: 846: 100.00
+	At
		221460 PHOT1_ARATH (156-1085): 4.08e-118: 390: 11.62		UBQ10_ARATH (305-685): 2.63e-153: 453: 95.80
+	At
		1091641 KIN10_ARATH (786-1079): 4.93e-115: 367: 14.29		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	At
		1091642 CDPKB_ARATH (755-1084): 8.27e-105: 339: 15.21		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	Hs
		474936 AKT2_HUMAN (743-1084): 3.35e-115: 366: 11.90		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70
+	Rn
		1144164 PAK2_RAT (581-1085): 3.72e-84: 284: 15.56		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Hs
		160345 AURKA_HUMAN (654-1065): 8.12e-81: 271: 15.09		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70
+	Mm
		250791 ULK1_MOUSE (782-1002): 2.51e-14: 79.8: 19.01		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Mm
		477068 PDPK1_MOUSE (772-1032): 5.21e-14: 78.3: 18.35		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74