HitPredict

Interactor 1: HTSF1 (O43719)
17S U2 SnRNP complex component HTATSF1 (HIV Tat-specific factor 1) (Tat-SF1)
Gene: HTATSF1

Interactor 2: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28977666
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PHD~RRM_1
Common GO terms	GO:0000724 - double-strand break repair via homologous recombination GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 755 Hs			1 1912
+	Hs
		212133 HTSF1_HUMAN (1-755): 2.64e-92: 306: 100.00		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		641776 U2AF2_HUMAN (129-356): 2.97e-32: 133: 22.03		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1031332 PABP4_HUMAN (62-285): 4.99e-31: 131: 12.66		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		516522 PABP1_HUMAN (62-264): 9.56e-30: 127: 12.14		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1059636 ELAV1_HUMAN (133-381): 1.21e-29: 122: 15.69		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		967177 EWS_HUMAN (126-217): 8.36e-16: 83.3: 26.60		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		726820 FUS_HUMAN (110-216): 7.15e-11: 67.5: 24.07		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Mm
		1142755 EWS_MOUSE (126-217): 4.96e-16: 84.1: 26.60		CHD4_MOUSE (1-1900): 0: 1680: 97.80
+	Hs
		641744 U2AF2_HUMAN (129-356): 2.97e-32: 133: 22.03		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1018458 PABP4_HUMAN (62-285): 4.99e-31: 131: 12.66		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		516483 PABP1_HUMAN (62-264): 9.56e-30: 127: 12.14		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1018502 ELAV1_HUMAN (133-381): 1.21e-29: 122: 15.69		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		967134 EWS_HUMAN (126-217): 8.36e-16: 83.3: 26.60		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		726779 FUS_HUMAN (110-216): 7.15e-11: 67.5: 24.07		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		642799 ELAV4_HUMAN (88-420): 8.56e-36: 141: 13.20		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Hs
		1020333 ELAV2_HUMAN (117-424): 7.45e-35: 138: 13.06		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Hs
		641946 U2AF2_HUMAN (129-356): 2.97e-32: 133: 22.03		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Mm
		1142756 EWS_MOUSE (126-217): 4.96e-16: 84.1: 26.60		SMCA1_MOUSE (557-1597): 0: 798: 27.05
+	Hs
		516702 PABP1_HUMAN (62-264): 9.56e-30: 127: 12.14		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Pf
		86920 C6KT30_PLAF7 (347-650): 5e-13: 75: 16.35		Q8IJG6_PLAF7 (542-1443): 0: 754: 31.15