Interactor 1: CIKS (O43734)
E3 ubiquitin ligase TRAF3IP2 (EC 2.3.2.27) (Adapter protein CIKS) (Connection to IKK and SAPK/JNK) (E3 ubiquitin-protein ligase CIKS) (Nuclear factor NF-kappa-B activator 1) (ACT1) (TRAF3-interacting protein 2)
Gene: TRAF3IP2
Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.60 | 0.761 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25202827, 23737552, 21516116, 30892082, 31174059, 32350852, 19825828, 12459498, 17277779, 25416956, 21822258, 22851696, 20953186 |
| Identification Methods | affinity chromatography technology, two hybrid, enzymatic study, pull down, two hybrid prey pooling approach, two hybrid array, validated two hybrid |
| Interaction Type | physical association, direct interaction, ubiquitination reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0031234 - extrinsic component of cytoplasmic side of plasma membrane GO:0033209 - tumor necrosis factor-mediated signaling pathway GO:0038173 - interleukin-17A-mediated signaling pathway and 4 others more... |
| Homologous interactions | 12 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
