HitPredict

Interactor 1: NIPBL (Q6KC79)
Nipped-B-like protein (Delangin) (SCC2 homolog)
Gene: NIPBL

Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37071664
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2804 Hs			1 1834
+	Hs
		854111 NIPBL_HUMAN (1-2804): 0: 2273: 100.00		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Hs
		1129646 MDC1_HUMAN (2-493): 1.53e-15: 86: 13.31		SLX4_HUMAN (1-1834): 0: 1473: 100.00
+	Hs
		535926 MYH3_HUMAN (590-1525): 5.23e-57: 222: 10.22		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Hs
		854008 IF4G1_HUMAN (104-1370): 5.27e-45: 182: 8.79		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Hs
		590235 MUC1_HUMAN (181-1206): 3.92e-28: 127: 7.65		MUC1_HUMAN (870-1755): 3.14e-23: 110: 10.32
+	Hs
		1403962 MUC4_HUMAN (36-1313): 6.54e-16: 87.5: 8.98		MUC4_HUMAN (850-1813): 9.84e-34: 145: 10.42
+	Hs
		854245 MINT_HUMAN (273-1226): 8.59e-22: 106: 13.49		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Dm
		119660 M9PB30_DROME (6-352): 4.1e-15: 84.8: 9.86		M9PB30_DROME (814-1463): 1.62e-28: 128: 10.28
+	Hs
		854056 MDC1_HUMAN (2-493): 1.53e-15: 86: 13.31		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Dm
		119668 Q9VC60_DROME (594-1181): 9.92e-09: 63: 14.21		M9PB30_DROME (814-1463): 1.62e-28: 128: 10.28
+	Hs
		1129658 BD1L1_HUMAN (466-1234): 6.6e-16: 87.2: 15.50		MDC1_HUMAN (757-1462): 4.4e-17: 90.6: 10.56
+	Hs
		1129588 MDC1_HUMAN (2-493): 1.53e-15: 86: 13.31		MDC1_HUMAN (757-1462): 4.4e-17: 90.6: 10.56
+	Hs
		161429 KMT2D_HUMAN (79-1033): 2.46e-09: 65.6: 10.07		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Hs
		861124 ANK2_HUMAN (5-1297): 9.91e-21: 103: 8.77		MAP1B_HUMAN (819-1706): 3.35e-10: 67.8: 10.90
+	Hs
		1129637 MDC1_HUMAN (2-493): 1.53e-15: 86: 13.31		MICA3_HUMAN (1139-1747): 8.47e-13: 76.3: 10.24
+	Mm
		1455913 PCLO_MOUSE (2-1382): 3.3e-10: 68.7: 9.09		PCLO_MOUSE (836-1825): 7.2e-16: 86.7: 10.09
+	Hs
		861240 PRG4_HUMAN (83-705): 2.56e-15: 85.1: 10.40		MAP1B_HUMAN (819-1706): 3.35e-10: 67.8: 10.90
+	Hs
		161492 BD1L1_HUMAN (466-1234): 6.6e-16: 87.2: 15.50		KMT2D_HUMAN (769-1409): 5.92e-09: 63.6: 9.52
+	Hs
		1091420 ANK3_HUMAN (10-1325): 2.17e-11: 72.5: 10.04		MICA3_HUMAN (1139-1747): 8.47e-13: 76.3: 10.24