HitPredict

Interactor 1: AP1G1 (O43747)
AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1)
Gene: AP1G1

Interactor 2: SYNRG (Q9UMZ2)
Synergin gamma (AP1 subunit gamma-binding protein 1) (Gamma-synergin)
Gene: SYNRG

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	12042876, 10814529, 15758025, 10747088
Identification Methods	pull down, two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0006886 - intracellular protein transport GO:0030121 - AP-1 adaptor complex GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 822 Hs			1 1314
+	Hs
		276397 AP1G2_HUMAN (6-822): 0: 690: 58.02		SYNRG_HUMAN (1-1314): 0: 2364: 100.00
+	Hs
		926053 AP2B1_HUMAN (30-800): 0: 552: 16.59		SYNRG_HUMAN (1-1314): 0: 2364: 100.00
+	Hs
		1014102 AP1B1_HUMAN (30-800): 0: 547: 17.36		SYNRG_HUMAN (1-1314): 0: 2364: 100.00
+	Rn
		923860 AP2B1_RAT (30-800): 0: 552: 16.59		SYNRG_RAT (27-196): 6.51e-97: 341: 94.12