HitPredict

Interactor 1: SGTA (O43765)
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT) (Vpu-binding protein) (UBP)
Gene: SGTA

Interactor 2: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	21988832
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HSP90~TPR_8
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 313 Hs			1 724
+	Hs
		213451 SGTA_HUMAN (1-313): 1.79e-68: 217: 100.00		HS90A_HUMAN (1-724): 0: 1072: 85.25
+	Mm
		513680 PPP5_MOUSE (66-233): 8.06e-41: 150: 28.57		HS90B_MOUSE (1-724): 0: 1089: 99.59
+	Hs
		438021 PPP5_HUMAN (66-233): 3.75e-40: 148: 28.57		HS90B_HUMAN (1-724): 0: 1086: 100.00
+	Hs
		438621 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		HS90B_HUMAN (1-724): 0: 1086: 100.00
+	Hs
		111935 PPP5_HUMAN (66-233): 3.75e-40: 148: 28.57		K9JA46_HUMAN (1-724): 0: 1072: 85.25
+	Hs
		431681 PPP5_HUMAN (66-233): 3.75e-40: 148: 28.57		HS90A_HUMAN (1-724): 0: 1072: 85.25
+	Hs
		432363 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		HS90A_HUMAN (1-724): 0: 1072: 85.25
+	Mm
		432427 PPP5_MOUSE (66-233): 8.06e-41: 150: 28.57		HS90A_MOUSE (1-724): 0: 1068: 84.31
+	Dm
		365470 Q9V3E9_DROME (3-239): 1.24e-38: 144: 22.63		HSP83_DROME (10-724): 0: 1057: 78.46
+	At
		99224 OE64M_ARATH (58-206): 1.1e-40: 151: 35.57		HS904_ARATH (10-724): 0: 1007: 66.85
+	At
		137805 OE64C_ARATH (45-204): 1.8e-39: 147: 30.00		HS904_ARATH (10-724): 0: 1007: 66.85
+	At
		99228 OE64M_ARATH (58-206): 1.1e-40: 151: 35.57		HS902_ARATH (10-724): 0: 1003: 66.85
+	At
		878283 OE64C_ARATH (45-204): 1.8e-39: 147: 30.00		HS902_ARATH (10-724): 0: 1003: 66.85
+	At
		99226 OE64M_ARATH (58-206): 1.1e-40: 151: 35.57		HS901_ARATH (10-724): 0: 999: 67.97
+	At
		646594 OE64C_ARATH (45-204): 1.8e-39: 147: 30.00		HS901_ARATH (10-724): 0: 999: 67.97
+	Hs
		538353 SGTB_HUMAN (1-311): 5.27e-54: 180: 57.24		ENPL_HUMAN (3-693): 0: 917: 46.44
+	Mm
		435924 PPP5_MOUSE (66-233): 8.06e-41: 150: 28.57		ENPL_MOUSE (3-724): 0: 920: 45.29
+	Zm
		33277 A0A1D6L1L3_MAIZE (45-195): 5.71e-41: 152: 33.78		A0A1D6LMW9_MAIZE (5-693): 0: 852: 46.66
+	Hs
		858632 PPP5_HUMAN (66-233): 3.75e-40: 148: 28.57		H90B4_HUMAN (25-596): 0: 639: 71.85
+	Hs
		1162522 Q9BPW0_HUMAN (66-233): 1.14e-40: 149: 28.57		Q6PK50_HUMAN (1-350): 0: 618: 99.71