HitPredict

Interactor 1: SGTA (O43765)
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT) (Vpu-binding protein) (UBP)
Gene: SGTA

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34349018, 16196087
Identification Methods	cross-linking study, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SGTA_dimer~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 313 Hs			1 685
+	Hs
		475516 TTC3_HUMAN (88-310): 3.46e-40: 151: 21.18		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476568 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475381 CDC27_HUMAN (6-246): 2.49e-24: 105: 16.60		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		174570 OGT1_HUMAN (83-311): 1.42e-22: 100: 14.41		UBC_HUMAN (1-685): 0: 846: 100.00
+	Pf
		1181548 HSOP_PLAF7 (90-263): 2.14e-17: 84.5: 22.40		Q7KQK2_PLAF7 (381-685): 3.65e-126: 380: 98.36
+	Sc
		477102 STI1_YEAST (46-213): 5.97e-15: 77.1: 26.71		UBI4P_YEAST (381-685): 5e-122: 370: 95.74
+	Hs
		213522 SGTA_HUMAN (1-313): 1.79e-68: 217: 100.00		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Rn
		251113 SGTA_RAT (1-313): 1.85e-66: 212: 88.54		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Rn
		1144228 SGTB_RAT (1-311): 4.58e-54: 180: 55.95		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Mm
		924235 PPP5_MOUSE (66-233): 8.06e-41: 150: 28.57		RS27A_MOUSE (609-684): 9.1e-41: 147: 100.00
+	Mm
		56866 CDC27_MOUSE (6-246): 1.76e-24: 105: 16.60		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Rn
		881491 OGT1_RAT (87-311): 1.01e-22: 100: 15.09		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Rn
		193485 STIP1_RAT (85-258): 8.8e-19: 88.4: 23.04		UBC_RAT (1-108): 1.27e-29: 127: 90.74