HitPredict

Interactor 1: VIP2 (O43314)
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 (EC 2.7.4.24) (Diphosphoinositol pentakisphosphate kinase 2) (Histidine acid phosphatase domain-containing protein 1) (InsP6 and PP-IP5 kinase 2) (VIP1 homolog 2) (hsVIP2)
Gene: PPIP5K2

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	33961781, 28514442, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1243 Hs			1 245
+	Hs
		213587 VIP2_HUMAN (1-1243): 0: 2077: 100.00		1433E_HUMAN (2-243): 1.32e-144: 406: 63.53
+	Hs
		213590 VIP2_HUMAN (1-1243): 0: 2077: 100.00		1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59
+	Hs
		213569 VIP2_HUMAN (1-1243): 0: 2077: 100.00		1433B_HUMAN (1-242): 5.04e-139: 391: 81.82
+	Hs
		213570 VIP2_HUMAN (1-1243): 0: 2077: 100.00		1433S_HUMAN (1-236): 9.9e-108: 312: 71.85
+	Hs
		213595 VIP2_HUMAN (1-1243): 0: 2077: 100.00		1433F_HUMAN (2-242): 7.19e-106: 307: 71.43
+	Hs
		213586 VIP2_HUMAN (1-1243): 0: 2077: 100.00		1433G_HUMAN (1-242): 5.51e-105: 305: 70.33
+	Hs
		729959 VIP1_HUMAN (43-1222): 0: 1779: 68.56		1433B_HUMAN (1-242): 5.04e-139: 391: 81.82
+	Hs
		966481 VIP1_HUMAN (43-1222): 0: 1779: 68.56		1433G_HUMAN (1-242): 5.51e-105: 305: 70.33
+	Ce
		1018991 VIP1_CAEEL (28-1053): 0: 1258: 49.63		14332_CAEEL (3-241): 2.1e-116: 334: 77.41
+	Ce
		836703 VIP1_CAEEL (28-1053): 0: 1258: 49.63		14331_CAEEL (5-236): 1.62e-109: 317: 77.59