Protein: VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 (EC 2.7.4.24) (Diphosphoinositol pentakisphosphate kinase 2) (Histidine acid phosphatase domain-containing protein 1) (InsP6 and PP-IP5 kinase 2) (VIP1 homolog 2) (hsVIP2)

Gene: VIP2, PPIP5K2
Organism: Homo sapiens
Interactions: 138
UniProt ID: O43314

Gene Ontology (top 5):
GO:0000827 - inositol-1,3,4,5,6-pentakisphosphate kinase activity
GO:0000828 - inositol hexakisphosphate kinase activity
GO:0000829 - diphosphoinositol pentakisphosphate kinase activity
GO:0000832 - inositol hexakisphosphate 5-kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

213597

CETN1
Centrin-1

3

1

High-throughput

0.662

High

213566

1433T
14-3-3 protein theta

3

10

High-throughput

0.643

High

213569

1433B
14-3-3 protein beta/alpha

3

10

High-throughput

0.643

High

213615

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1

1

1

High-throughput

0.618

High

213586

1433G
14-3-3 protein gamma

2

10

High-throughput

0.601

High

213595

1433F
14-3-3 protein eta

2

10

High-throughput

0.601

High

213599

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

2

1

High-throughput

0.601

High

213642

NUP88
Nuclear pore complex protein Nup88

2

1

High-throughput

0.584

High

213561

PO2F1
POU domain, class 2, transcription factor 1

2

1

High-throughput

0.553

High

213591

PO6F2
POU domain, class 6, transcription factor 2

2

1

High-throughput

0.553

High

213636

SMRC1
SWI/SNF complex subunit SMARCC1

2

1

High-throughput

0.553

High

213617

DNMBP
Dynamin-binding protein

2

0

High-throughput

0.547

High

213572

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.536

High

213583

COPA
Coatomer subunit alpha

1

1

High-throughput

0.536

High

213590

1433Z
14-3-3 protein zeta/delta

1

10

High-throughput

0.536

High

213606

TEBP
Prostaglandin E synthase 3

1

1

High-throughput

0.536

High

213647

DUS16
Dual specificity protein phosphatase 16

1

1

High-throughput

0.536

High

158056

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.513

High

177139

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

0

High-throughput

0.513

High

213550

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

213563

CAN2
Calpain-2 catalytic subunit

1

0

High-throughput

0.513

High

213584

MANF
Mesencephalic astrocyte-derived neurotrophic factor

1

0

High-throughput

0.493

High

213624

PIAS4
E3 SUMO-protein ligase PIAS4

1

1

High-throughput

0.489

High

213570

1433S
14-3-3 protein sigma

1

10

High-throughput

0.479

High

213612

GRDN
Girdin

1

1

High-throughput

0.479

High

213633

BICD2
Protein bicaudal D homolog 2

1

1

High-throughput

0.479

High

213548

SC24B
Protein transport protein Sec24B

1

0

High-throughput

0.458

High

213554

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

213555

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

213573

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

213581

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

213587

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.458

High

213588

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

0

High-throughput

0.458

High

213596

AHNK
Neuroblast differentiation-associated protein AHNAK

1

0

High-throughput

0.458

High

213604

EEA1
Early endosome antigen 1

1

0

High-throughput

0.458

High

213605

PLEC
Plectin

1

0

High-throughput

0.458

High

213611

AAK1
AP2-associated protein kinase 1

1

0

High-throughput

0.458

High

213632

URGCP
Up-regulator of cell proliferation

1

0

High-throughput

0.458

High

213653

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

213655

ARFG3
ADP-ribosylation factor GTPase-activating protein 3

1

0

High-throughput

0.458

High

48449

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.445

High

213556

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

3

High-throughput

0.445

High

213559

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.445

High

213567

CALR
Calreticulin

1

1

High-throughput

0.445

High

213621

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

1

High-throughput

0.445

High

213623

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

1

High-throughput

0.445

High

213627

DHB11
Estradiol 17-beta-dehydrogenase 11

1

2

High-throughput

0.445

High

213640

SCYL1
N-terminal kinase-like protein

1

2

High-throughput

0.445

High

213662

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.445

High

213663

COPG2
Coatomer subunit gamma-2

1

1

High-throughput

0.445

High

213668

COPG1
Coatomer subunit gamma-1

1

1

High-throughput

0.445

High

74398

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

3

High-throughput

0.437

High

85520

HNRC3
Heterogeneous nuclear ribonucleoprotein C-like 3

1

3

High-throughput

0.437

High

213541

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

3

High-throughput

0.437

High

213549

EYA4
Protein phosphatase EYA4

1

1

High-throughput

0.437

High

213622

LUZP1
Leucine zipper protein 1

1

3

High-throughput

0.437

High

60268

NBAS
NBAS subunit of NRZ tethering complex

1

0

High-throughput

0.426

High

211691

ZW10
Centromere/kinetochore protein zw10 homolog

1

0

High-throughput

0.426

High

213544

STAM2
Signal transducing adapter molecule 2

1

0

High-throughput

0.426

High

213551

NB5R3
NADH-cytochrome b5 reductase 3

1

0

High-throughput

0.426

High

213558

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

213574

COPD
Coatomer subunit delta

1

0

High-throughput

0.426

High

213575

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.426

High

213577

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

0

High-throughput

0.426

High

213580

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.426

High

213582

COPB
Coatomer subunit beta

1

0

High-throughput

0.426

High

213585

COPZ1
Coatomer subunit zeta-1

1

0

High-throughput

0.426

High

213589

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

0

High-throughput

0.426

High

213592

NUCB2
Nucleobindin-2

1

0

High-throughput

0.426

High

213598

PRDX4
Peroxiredoxin-4

1

0

High-throughput

0.426

High

213602

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.426

High

213603

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.426

High

213616

LCLT1
Lysocardiolipin acyltransferase 1

1

0

High-throughput

0.426

High

213629

VP37A
Vacuolar protein sorting-associated protein 37A

1

0

High-throughput

0.426

High

213634

SCFD1
Sec1 family domain-containing protein 1

1

0

High-throughput

0.426

High

213638

ASTRA
Protein Aster-A

1

0

High-throughput

0.426

High

213641

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

213648

WDR11
WD repeat-containing protein 11

1

0

High-throughput

0.426

High

213650

RGAP1
Rac GTPase-activating protein 1

1

0

High-throughput

0.426

High

213651

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.426

High

213667

SERC
Phosphoserine aminotransferase

1

0

High-throughput

0.426

High

104305

F5H6I7
Atlastin GTPase 3

1

2

High-throughput

0.407

High

213542

RTN2
Reticulon-2

1

2

High-throughput

0.407

High

213545

MICA2
[F-actin]-monooxygenase MICAL2

1

1

High-throughput

0.407

High

213546

RTN3
Reticulon-3

1

2

High-throughput

0.407

High

213547

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

High-throughput

0.407

High

213568

CALX
Calnexin

1

1

High-throughput

0.407

High

213578

TMEDA
Transmembrane emp24 domain-containing protein 10

1

2

High-throughput

0.407

High

213608

TMED2
Transmembrane emp24 domain-containing protein 2

1

2

High-throughput

0.407

High

213609

DHC24
Delta(24)-sterol reductase

1

1

High-throughput

0.407

High

213613

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

2

High-throughput

0.407

High

213620

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

1

High-throughput

0.407

High

213630

ATLA2
Atlastin-2

1

2

High-throughput

0.407

High

213635

ATLA1
Atlastin-1

1

2

High-throughput

0.407

High

213645

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.407

High

213652

TMX1
Thioredoxin-related transmembrane protein 1

1

1

High-throughput

0.407

High

213656

RTN4
Reticulon-4

1

2

High-throughput

0.407

High

213660

PSD3
PH and SEC7 domain-containing protein 3

1

1

High-throughput

0.407

High

213665

DHRS7
Dehydrogenase/reductase SDR family member 7

1

1

High-throughput

0.407

High

213666

TMED5
Transmembrane emp24 domain-containing protein 5

1

2

High-throughput

0.407

High

213557

CEL3A
Chymotrypsin-like elastase family member 3A

2

0

High-throughput

0.328

High

213618

DEFI8
Differentially expressed in FDCP 8 homolog

2

0

High-throughput

0.328

High

213565

IL3RA
Interleukin-3 receptor subunit alpha

1

0

High-throughput

0.279

Low

213614

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

1

0

High-throughput

0.279

Low

213639

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.279

Low

213564

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

0

High-throughput

0.269

Low

213553

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.249

Low

213562

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

213571

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

213576

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

213619

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

213664

XPO7
Exportin-7

1

0

High-throughput

0.249

Low

50447

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.232

Low

213540

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.232

Low

213543

ERLN1
Erlin-1

1

0

High-throughput

0.232

Low

213552

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.232

Low

213560

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.232

Low

213579

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.232

Low

213593

ARF5
ADP-ribosylation factor 5

1

0

High-throughput

0.232

Low

213594

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.232

Low

213600

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.232

Low

213601

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.232

Low

213607

RCN1
Reticulocalbin-1

1

0

High-throughput

0.232

Low

213610

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.232

Low

213625

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

High-throughput

0.232

Low

213626

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.232

Low

213628

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.232

Low

213631

MCFD2
Multiple coagulation factor deficiency protein 2

1

0

High-throughput

0.232

Low

213637

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.232

Low

213643

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.232

Low

213644

ERP44
Endoplasmic reticulum resident protein 44

1

0

High-throughput

0.232

Low

213646

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.232

Low

213649

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.232

Low

213654

APMAP
Adipocyte plasma membrane-associated protein

1

0

High-throughput

0.232

Low

213657

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.232

Low

213658

TM38B
Trimeric intracellular cation channel type B

1

0

High-throughput

0.232

Low

213659

GPTC2
G patch domain-containing protein 2

1

0

High-throughput

0.232

Low

213661

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025