HitPredict

Interactor 1: SGTA (O43765)
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT) (Vpu-binding protein) (UBP)
Gene: SGTA

Interactor 2: DJB12 (Q9NXW2)
DnaJ homolog subfamily B member 12
Gene: DNAJB12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25036637
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0036503 - ERAD pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 313 Hs			1 375
+	Hs
		213601 SGTA_HUMAN (1-313): 1.79e-68: 217: 100.00		DJB14_HUMAN (1-375): 1.97e-123: 362: 51.32
+	Hs
		1348103 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		DJB12_HUMAN (1-375): 1.18e-140: 406: 100.00
+	Hs
		1252953 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		DJB14_HUMAN (1-375): 1.97e-123: 362: 51.32
+	Hs
		213644 SGTA_HUMAN (1-313): 1.79e-68: 217: 100.00		DJC18_HUMAN (51-375): 5.94e-85: 263: 39.71
+	Hs
		1333332 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		DJC18_HUMAN (51-375): 5.94e-85: 263: 39.71
+	Dm
		1366858 Q9VH81_DROME (65-204): 3.01e-41: 151: 32.14		Q9VS57_DROME (51-373): 7.6e-45: 166: 15.90
+	Hs
		279360 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		DNJB5_HUMAN (109-250): 8.83e-46: 162: 36.62
+	Hs
		1290536 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		DNJA3_HUMAN (102-261): 2.09e-43: 158: 32.30
+	Hs
		258247 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		DNJB6_HUMAN (110-215): 1.44e-43: 155: 47.71
+	Hs
		279295 FKBP5_HUMAN (16-262): 7.6e-37: 138: 17.49		DNJB5_HUMAN (109-250): 8.83e-46: 162: 36.62
+	Hs
		636443 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		DNJB1_HUMAN (109-251): 2.52e-42: 152: 37.42
+	Hs
		858603 PPP5_HUMAN (66-233): 3.75e-40: 148: 28.57		DJB13_HUMAN (109-243): 5.53e-42: 151: 35.04
+	Hs
		1245931 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		DNJB8_HUMAN (110-249): 2.46e-42: 149: 36.11
+	Hs
		258010 FKBP5_HUMAN (16-262): 7.6e-37: 138: 17.49		DNJB6_HUMAN (110-215): 1.44e-43: 155: 47.71
+	Hs
		887185 FKBP5_HUMAN (16-262): 7.6e-37: 138: 17.49		DJB13_HUMAN (109-243): 5.53e-42: 151: 35.04
+	Hs
		1034936 FKBP5_HUMAN (16-262): 7.6e-37: 138: 17.49		DNJB8_HUMAN (110-249): 2.46e-42: 149: 36.11
+	Hs
		1262156 SGTB_HUMAN (1-311): 5.27e-54: 180: 57.24		DNJA4_HUMAN (111-211): 4.34e-18: 86.7: 52.48
+	Hs
		257927 STIP1_HUMAN (85-258): 2.08e-19: 90.3: 24.08		DNJB6_HUMAN (110-215): 1.44e-43: 155: 47.71
+	Hs
		1354291 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		DJB11_HUMAN (109-189): 1.2e-18: 88.2: 53.66
+	Hs
		1262171 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		DNJA4_HUMAN (111-211): 4.34e-18: 86.7: 52.48