HitPredict

Interactor 1: KRT86 (O43790)
Keratin, type II cuticular Hb6 (Hair keratin K2.11) (Keratin-86) (K86) (Type II hair keratin Hb6) (Type-II keratin Kb26)
Gene: KRT86

Interactor 2: NFM (P07197)
Neurofilament medium polypeptide (NF-M) (160 kDa neurofilament protein) (Neurofilament 3) (Neurofilament triplet M protein)
Gene: NEFM

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 486 Hs			1 916
+	Hs
		213937 KRT86_HUMAN (1-486): 6.11e-115: 349: 100.00		K22O_HUMAN (93-413): 3.56e-138: 428: 31.89
+	Hs
		444539 K2C7_HUMAN (22-461): 5.84e-160: 463: 50.91		AINX_HUMAN (8-494): 2.98e-91: 300: 47.69
+	Hs
		422128 K2C7_HUMAN (22-461): 5.84e-160: 463: 50.91		NFL_HUMAN (74-420): 2.2e-73: 253: 53.16
+	Hs
		422328 K2C7_HUMAN (22-461): 5.84e-160: 463: 50.91		NFM_HUMAN (1-916): 4.85e-65: 237: 100.00
+	Hs
		409089 K2C8_HUMAN (78-443): 3.96e-117: 354: 56.83		AINX_HUMAN (8-494): 2.98e-91: 300: 47.69
+	Hs
		408979 K2C8_HUMAN (78-443): 3.96e-117: 354: 56.83		VIME_HUMAN (8-413): 1.85e-77: 261: 44.61
+	Hs
		380550 K2C1_HUMAN (75-431): 4.15e-124: 377: 54.44		GFAP_HUMAN (94-413): 1.96e-67: 233: 48.44
+	Hs
		280768 K2C1_HUMAN (75-431): 4.15e-124: 377: 54.44		KRT36_HUMAN (2-412): 2.38e-61: 217: 29.61
+	Hs
		380657 K2C1_HUMAN (75-431): 4.15e-124: 377: 54.44		KRT35_HUMAN (6-417): 6.92e-61: 216: 29.30
+	Hs
		408975 K2C8_HUMAN (78-443): 3.96e-117: 354: 56.83		NFM_HUMAN (1-916): 4.85e-65: 237: 100.00
+	Hs
		408991 K2C8_HUMAN (78-443): 3.96e-117: 354: 56.83		GFAP_HUMAN (94-413): 1.96e-67: 233: 48.44
+	Hs
		409072 K2C8_HUMAN (78-443): 3.96e-117: 354: 56.83		K1H2_HUMAN (10-419): 7.09e-65: 226: 26.28
+	Hs
		380645 K2C1_HUMAN (75-431): 4.15e-124: 377: 54.44		K1C28_HUMAN (7-472): 3.64e-55: 200: 24.42
+	Hs
		213947 KRT86_HUMAN (1-486): 6.11e-115: 349: 100.00		K1H2_HUMAN (10-419): 7.09e-65: 226: 26.28
+	Hs
		280770 K2C8_HUMAN (78-443): 3.96e-117: 354: 56.83		KRT36_HUMAN (2-412): 2.38e-61: 217: 29.61
+	Hs
		409022 K2C8_HUMAN (78-443): 3.96e-117: 354: 56.83		PERI_HUMAN (43-413): 2.9e-61: 217: 46.51
+	Hs
		409184 K2C8_HUMAN (78-443): 3.96e-117: 354: 56.83		KRT35_HUMAN (6-417): 6.92e-61: 216: 29.30
+	Hs
		213919 KRT86_HUMAN (1-486): 6.11e-115: 349: 100.00		KRT36_HUMAN (2-412): 2.38e-61: 217: 29.61
+	Hs
		409134 K2C8_HUMAN (78-443): 3.96e-117: 354: 56.83		K1C28_HUMAN (7-472): 3.64e-55: 200: 24.42
+	Hs
		408987 K2C8_HUMAN (78-443): 3.96e-117: 354: 56.83		MYH1_HUMAN (411-916): 1.62e-16: 87.2: 8.95