HitPredict

Interactor 1: STRN (O43815)
Striatin
Gene: STRN

Interactor 2: 2AAB (P30154)
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A subunit A isoform PR65-beta) (PP2A subunit A isoform R1-beta)
Gene: PPP2R1B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.932

Property	Details
Experiments	24366813, 26496610, 18782753, 33961781, 17540176
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	HEAT_2~Striatin
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 780 Hs			1 601
+	Hs
		215198 STRN_HUMAN (1-780): 0: 650: 100.00		2AAA_HUMAN (14-601): 3.9e-172: 503: 86.22
+	Hs
		672100 STRN3_HUMAN (33-780): 0: 580: 63.56		2AAA_HUMAN (14-601): 3.9e-172: 503: 86.22
+	Hs
		672413 STRN3_HUMAN (33-780): 0: 580: 63.56		2AAB_HUMAN (1-601): 8.13e-170: 497: 100.00
+	Hs
		672152 Q59GV6_HUMAN (5-733): 2.04e-123: 389: 24.58		2AAA_HUMAN (14-601): 3.9e-172: 503: 86.22
+	Dm
		87968 D3DML3_DROME (40-780): 3.97e-129: 404: 42.57		2AAA_DROME (11-590): 7.14e-155: 459: 71.72
+	Hs
		672317 STRN4_HUMAN (5-642): 2.34e-105: 341: 26.51		2AAA_HUMAN (14-601): 3.9e-172: 503: 86.22
+	Hs
		672479 STRN4_HUMAN (5-642): 2.34e-105: 341: 26.51		2AAB_HUMAN (1-601): 8.13e-170: 497: 100.00
+	Hs
		672078 RACK1_HUMAN (449-779): 4.95e-75: 247: 21.66		2AAA_HUMAN (14-601): 3.9e-172: 503: 86.22
+	Dm
		734229 Q9VLT9_DROME (451-780): 1.02e-86: 291: 63.64		2AAA_DROME (11-590): 7.14e-155: 459: 71.72
+	Hs
		672284 TBL1R_HUMAN (128-494): 1.14e-19: 95.2: 8.30		2AAA_HUMAN (14-601): 3.9e-172: 503: 86.22
+	Hs
		245645 TBL1X_HUMAN (429-779): 1.7e-83: 279: 21.56		PP4RL_HUMAN (272-485): 1.28e-10: 65.8: 18.81
+	Hs
		268646 WDR5_HUMAN (297-642): 1.8e-62: 215: 12.08		SF3B1_HUMAN (147-580): 4.07e-18: 90.6: 13.84
+	Hs
		903400 WDR5_HUMAN (297-642): 1.8e-62: 215: 12.08		GCN1_HUMAN (20-600): 6.38e-12: 71: 14.37
+	Hs
		980822 TLE3_HUMAN (294-598): 4.74e-28: 122: 12.22		PP4R1_HUMAN (337-595): 6.3e-09: 61.2: 17.78
+	Hs
		268815 SNR40_HUMAN (508-779): 4.85e-16: 82.4: 25.54		SF3B1_HUMAN (147-580): 4.07e-18: 90.6: 13.84
+	Hs
		1318184 TBL1R_HUMAN (128-494): 1.14e-19: 95.2: 8.30		PP4RL_HUMAN (272-485): 1.28e-10: 65.8: 18.81