Protein: TXN4A
Thioredoxin-like protein 4A (DIM1 protein homolog) (Spliceosomal U5 snRNP-specific 15 kDa protein) (Thioredoxin-like U5 snRNP protein U5-15kD)

Gene: TXN4A, TXNL4A
Organism: Homo sapiens
Interactions: 74
UniProt ID: P83876

Gene Ontology (top 5):
GO:0000245 - spliceosomal complex assembly
GO:0000375 - RNA splicing, via transesterification reactions
GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

321498

PRP6
Pre-mRNA-processing factor 6

4

3

Small-scale

0.905

High

335815

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

6

0

Small-scale

0.904

High

1013951

PRP8
Pre-mRNA-processing-splicing factor 8

4

1

High-throughput

0.895

High

1013965

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

4

2

High-throughput

0.699

High

1013946

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

1

High-throughput

0.691

High

1013970

RBM42
RNA-binding protein 42

1

1

High-throughput

0.691

High

973884

RUXF
Small nuclear ribonucleoprotein F

3

7

High-throughput

0.675

High

250548

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.656

High

477997

SNRPA
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.656

High

480093

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.656

High

1013941

RBM39
RNA-binding protein 39

1

0

High-throughput

0.656

High

1013945

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.656

High

1013971

DDX23
Probable ATP-dependent RNA helicase DDX23

3

0

High-throughput

0.638

High

1013977

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

3

0

High-throughput

0.638

High

574217

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

2

High-throughput

0.628

High

991167

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

2

High-throughput

0.628

High

1013942

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

2

1

High-throughput

0.628

High

1013958

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

1

High-throughput

0.621

High

257240

PQBP1
Polyglutamine-binding protein 1

3

0

Small-scale

0.612

High

974115

RUXG
Small nuclear ribonucleoprotein G

2

8

High-throughput

0.611

High

912842

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

0

Small-scale

0.589

High

1013963

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.589

High

1013975

RBM22
Pre-mRNA-splicing factor RBM22

1

0

High-throughput

0.589

High

472641

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.586

High

137214

EXOC5
Exocyst complex component 5

1

0

High-throughput

0.549

High

1013969

LZTS2
Leucine zipper putative tumor suppressor 2

1

0

High-throughput

0.549

High

209248

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

2

High-throughput

0.536

High

215080

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

1

2

High-throughput

0.536

High

289503

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

2

High-throughput

0.536

High

973690

RUXE
Small nuclear ribonucleoprotein E

1

2

High-throughput

0.536

High

974522

SMD2
Small nuclear ribonucleoprotein Sm D2

1

2

High-throughput

0.536

High

974719

SMD3
Small nuclear ribonucleoprotein Sm D3

1

5

High-throughput

0.536

High

641571

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

1

High-throughput

0.526

High

221848

CHM2A
Charged multivesicular body protein 2a

1

0

High-throughput

0.513

High

231390

PDE6D
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta

1

0

High-throughput

0.513

High

285873

SF3B1
Splicing factor 3B subunit 1

1

0

High-throughput

0.513

High

375401

RASK
GTPase KRas

1

0

High-throughput

0.513

High

479796

GSTP1
Glutathione S-transferase P

1

0

High-throughput

0.513

High

541945

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

592833

CBR1
Carbonyl reductase [NADPH] 1

1

0

High-throughput

0.513

High

832301

ID1
DNA-binding protein inhibitor ID-1

1

0

High-throughput

0.513

High

1013937

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

1013939

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

0

High-throughput

0.513

High

1013948

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

0

High-throughput

0.513

High

1013952

UBP43
Ubiquitin carboxyl-terminal hydrolase 43

1

0

High-throughput

0.513

High

1013968

TSNAX
Translin-associated protein X

1

0

High-throughput

0.513

High

1013959

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

1

High-throughput

0.481

High

1013967

QKI
KH domain-containing RNA-binding protein QKI

1

1

High-throughput

0.481

High

1013938

EP300
Histone acetyltransferase p300

1

1

High-throughput

0.479

High

1013943

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

1013950

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.479

High

1013962

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1013940

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.460

High

1013944

K1H1
Keratin, type I cuticular Ha1

1

0

High-throughput

0.460

High

1013953

LARP4
La-related protein 4

1

0

High-throughput

0.460

High

1013966

DMRTB
Doublesex- and mab-3-related transcription factor B1

1

0

High-throughput

0.460

High

222939

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

418939

H2A1B
Histone H2A type 1-B/E

1

0

High-throughput

0.458

High

1013956

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1013957

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

1

0

Small-scale

0.458

High

1013973

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

1013976

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

71573

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

8

High-throughput

0.445

High

1013961

REBL1
GTPase RhebL1

2

0

Small-scale

0.329

High

1013964

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.316

High

463941

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

0

High-throughput

0.279

Low

838487

GRIA2
Glutamate receptor 2

1

0

High-throughput

0.279

Low

1013947

TPD53
Tumor protein D53

1

0

High-throughput

0.279

Low

1013972

KIFC3
Kinesin-like protein KIFC3

1

0

High-throughput

0.279

Low

1013949

PRC2B
Protein PRRC2B

1

0

High-throughput

0.251

Low

1013955

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

0

High-throughput

0.251

Low

1013974

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

0

High-throughput

0.251

Low

1013954

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low

1013960

IL31R
Interleukin-31 receptor subunit alpha

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025