Protein: PRP3
U4/U6 small nuclear ribonucleoprotein PRP3 (Pre-mRNA-splicing factor 3)

Gene: PRP3
Organism: Saccharomyces cerevisiae S288C
Interactions: 54
UniProt ID: Q03338

Gene Ontology (top 5):
GO:0000245 - spliceosomal complex assembly
GO:0000387 - spliceosomal snRNP assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

627868

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

7

4

Small-scale

0.972

High

751779

PRP8
Pre-mRNA-splicing factor 8

5

1

Small-scale

0.922

High

945346

LSM3
LSM complex subunit LSM3

5

12

Small-scale

0.915

High

865280

LSM8
LSM2-LSM8 complex subunit LSM8

4

9

Small-scale

0.896

High

820831

RUXG
Small nuclear ribonucleoprotein G

4

8

High-throughput

0.881

High

1042454

LSM6
LSM complex subunit LSM6

3

3

High-throughput

0.861

High

818047

LSM4
LSM complex subunit LSM4

3

3

High-throughput

0.855

High

817152

RSMB
Small nuclear ribonucleoprotein-associated protein B

3

2

High-throughput

0.847

High

847823

SMD3
Small nuclear ribonucleoprotein Sm D3

3

7

Small-scale

0.847

High

795917

LSM2
LSM complex subunit LSM2

2

7

High-throughput

0.789

High

1036169

SMD1
Small nuclear ribonucleoprotein Sm D1

2

1

High-throughput

0.789

High

1042453

SMD2
Small nuclear ribonucleoprotein Sm D2

2

1

High-throughput

0.789

High

933133

RUXF
Small nuclear ribonucleoprotein F

2

3

High-throughput

0.776

High

1042452

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

2

2

Small-scale

0.754

High

744154

BRR2
Pre-mRNA-splicing helicase BRR2

8

3

Small-scale

0.746

High

625042

PRP6
Pre-mRNA-splicing factor 6

5

2

High-throughput

0.718

High

780214

SN114
Pre-mRNA-splicing factor SNU114

4

1

High-throughput

0.694

High

886351

PRP31
Pre-mRNA-processing factor 31

4

2

High-throughput

0.694

High

1042464

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

4

1

Small-scale

0.691

High

797319

SP381
Pre-mRNA-splicing factor SPP381

3

0

High-throughput

0.634

High

739268

PRP21
Pre-mRNA-splicing factor PRP21

1

1

High-throughput

0.618

High

818481

LSM5
LSM complex subunit LSM5

1

1

High-throughput

0.618

High

924555

LSM7
LSM complex subunit LSM7

1

10

High-throughput

0.618

High

1042462

RUXE
Small nuclear ribonucleoprotein E

1

1

High-throughput

0.618

High

1042457

DIB1
Spliceosomal protein DIB1

2

2

High-throughput

0.611

High

1042455

ATG17
Autophagy-related protein 17

2

0

High-throughput

0.594

High

892779

SF3B1
U2 snRNP component HSH155

2

1

Small-scale

0.586

High

1026946

PRP38
Pre-mRNA-splicing factor 38

2

0

High-throughput

0.585

High

1042463

SNU23
23 kDa U4/U6.U5 small nuclear ribonucleoprotein component

2

0

High-throughput

0.585

High

722210

XPO1
Exportin-1

1

0

High-throughput

0.513

High

794329

PBP2
PAB1-binding protein 2

1

1

High-throughput

0.508

High

713030

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.486

High

628225

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

1

1

High-throughput

0.470

High

666706

GRR1
SCF E3 ubiquitin ligase complex F-box protein GRR1

1

0

Small-scale

0.460

High

708014

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

709953

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

781582

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.458

High

1042458

NCBP2
Nuclear cap-binding protein subunit 2

1

0

High-throughput

0.458

High

1042459

RU2A
U2 small nuclear ribonucleoprotein A'

1

0

High-throughput

0.458

High

727279

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

739192

PRP19
Pre-mRNA-processing factor 19

1

3

Small-scale

0.445

High

742273

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

602617

PHO85
Cyclin-dependent protein kinase PHO85

1

0

High-throughput

0.438

High

1042456

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.438

High

524970

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

804410

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

819636

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.426

High

752665

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

790374

STT4
Phosphatidylinositol 4-kinase STT4

1

0

High-throughput

0.269

Low

877890

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.269

Low

654801

URE2
Transcriptional regulator URE2

1

0

High-throughput

0.265

Low

1042461

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

0

High-throughput

0.265

Low

1042460

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025