HitPredict

Interactor 1: COCH (O43405)
Cochlin (COCH-5B2)
Gene: COCH

Interactor 2: VITRN (Q6UXI7)
Vitrin
Gene: VIT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	VWA~VWA
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 550 Hs			1 678
+	Hs
		407744 VWF_HUMAN (17-546): 4.36e-58: 211: 15.20		VWF_HUMAN (63-672): 1.36e-112: 375: 16.26
+	Hs
		641996 ITA1_HUMAN (276-550): 3.1e-59: 214: 20.53		MATN1_HUMAN (80-486): 4.51e-78: 259: 14.29
+	Hs
		183384 MATN3_HUMAN (361-548): 2.26e-57: 201: 28.50		MATN1_HUMAN (80-486): 4.51e-78: 259: 14.29
+	Hs
		1052182 COKA1_HUMAN (313-550): 4.44e-57: 208: 25.51		COEA1_HUMAN (274-481): 3.31e-52: 197: 24.40
+	Hs
		1052170 COEA1_HUMAN (361-545): 4.59e-55: 203: 33.51		COLA1_HUMAN (281-501): 7.48e-52: 195: 26.11
+	Hs
		132958 MATN2_HUMAN (150-358): 1.72e-51: 191: 23.11		CFAB_HUMAN (490-677): 1.78e-35: 145: 18.92
+	Mm
		97712 E9PWQ3_MOUSE (338-541): 1.01e-40: 160: 26.79		E9PWQ3_MOUSE (493-676): 2.3e-39: 158: 24.87
+	Hs
		132993 MATN1_HUMAN (350-546): 1.26e-54: 193: 23.27		MATN2_HUMAN (88-292): 1.01e-22: 105: 8.93
+	Hs
		132948 MATN2_HUMAN (150-358): 1.72e-51: 191: 23.11		MATN2_HUMAN (88-292): 1.01e-22: 105: 8.93
+	Hs
		132953 MATN4_HUMAN (150-356): 1.11e-52: 191: 20.48		MATN2_HUMAN (88-292): 1.01e-22: 105: 8.93
+	Hs
		337505 MATN1_HUMAN (350-546): 1.26e-54: 193: 23.27		MATN4_HUMAN (78-262): 1.12e-13: 76.4: 8.91
+	Mm
		1224637 CO7A1_MOUSE (356-549): 3.56e-21: 100: 15.50		CO7A1_MOUSE (461-669): 3.23e-20: 98.3: 17.97