Protein: MYD88
Myeloid differentiation primary response protein MyD88

Gene: MYD88
Organism: Mus musculus
Interactions: 66
UniProt ID: P22366

Gene Ontology (top 5):
GO:0002238 - response to molecule of fungal origin
GO:0002269 - leukocyte activation involved in inflammatory response
GO:0002283 - neutrophil activation involved in immune response
GO:0002755 - MyD88-dependent toll-like receptor signaling pathway
GO:0005102 - signaling receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

607559

IRAK1
Interleukin-1 receptor-associated kinase 1

9

20

Small-scale

0.968

High

607532

MYD88
Myeloid differentiation primary response protein MyD88

3

20

Small-scale

0.850

High

607565

IRAK2
Interleukin-1 receptor-associated kinase-like 2

3

20

Small-scale

0.827

High

607581

TLR4
Toll-like receptor 4

15

20

Small-scale

0.759

High

607575

TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein

2

6

Small-scale

0.754

High

607543

TRAF6
TNF receptor-associated factor 6

8

18

Small-scale

0.746

High

607570

IRAK4
Interleukin-1 receptor-associated kinase 4

6

20

Small-scale

0.728

High

140019

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

Small-scale

0.724

High

607554

TRAF3
TNF receptor-associated factor 3

3

19

Small-scale

0.670

High

528283

IL1R1
Interleukin-1 receptor type 1

3

13

Small-scale

0.650

High

547379

IRF1
Interferon regulatory factor 1

3

20

Small-scale

0.650

High

607537

IRF5
Interferon regulatory factor 5

3

20

Small-scale

0.650

High

607545

IRF7
Interferon regulatory factor 7

3

20

Small-scale

0.640

High

607582

TLR2
Toll-like receptor 2

3

20

Small-scale

0.640

High

607550

CBLB
E3 ubiquitin-protein ligase CBL-B

2

2

Small-scale

0.621

High

607555

FADD
FAS-associated death domain protein

1

7

Small-scale

0.618

High

607584

TNIP1
TNFAIP3-interacting protein 1

2

2

Small-scale

0.611

High

607577

TLR9
Toll-like receptor 9

2

20

Small-scale

0.586

High

607580

FLII
Protein flightless-1 homolog

2

1

Small-scale

0.584

High

607569

IRAK3
Interleukin-1 receptor-associated kinase 3

1

20

Small-scale

0.575

High

607535

BTK
Tyrosine-protein kinase BTK

1

15

Small-scale

0.536

High

607536

KSYK
Tyrosine-protein kinase SYK

1

20

Small-scale

0.536

High

607578

TR13B
Tumor necrosis factor receptor superfamily member 13B

1

1

Small-scale

0.536

High

607562

RNF41
E3 ubiquitin-protein ligase NRDP1

1

18

Small-scale

0.528

High

291951

BECN1
Beclin-1

1

1

Small-scale

0.515

High

607548

TF65
Transcription factor p65

1

1

Small-scale

0.515

High

607557

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

4

Small-scale

0.515

High

607560

IRF4
Interferon regulatory factor 4

1

20

Small-scale

0.515

High

607576

BCAP
Phosphoinositide 3-kinase adapter protein 1

1

6

Small-scale

0.515

High

489472

BCL2
Apoptosis regulator Bcl-2

1

0

Small-scale

0.493

High

476687

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

2

Small-scale

0.479

High

588701

BIP
Endoplasmic reticulum chaperone BiP

1

7

Small-scale

0.479

High

607533

IRF2
Interferon regulatory factor 2

1

20

Small-scale

0.479

High

607534

FAK1
Focal adhesion kinase 1

1

14

Small-scale

0.479

High

607538

ARL1
ADP-ribosylation factor-like protein 1

1

2

Small-scale

0.479

High

607539

HSP7C
Heat shock cognate 71 kDa protein

1

6

Small-scale

0.479

High

607541

TBB4B
Tubulin beta-4B chain

1

6

Small-scale

0.479

High

607542

TBA1C
Tubulin alpha-1C chain

1

5

Small-scale

0.479

High

607547

TBB5
Tubulin beta-5 chain

1

6

Small-scale

0.479

High

607549

EPS8
Epidermal growth factor receptor kinase substrate 8

1

6

Small-scale

0.479

High

607551

LRRF1
Leucine-rich repeat flightless-interacting protein 1

1

3

Small-scale

0.479

High

607553

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

1

Small-scale

0.479

High

607556

IL1AP
Interleukin-1 receptor accessory protein

1

20

Small-scale

0.479

High

607561

SQSTM
Sequestosome-1

1

2

Small-scale

0.479

High

607567

I17RD
Interleukin-17 receptor D

1

2

Small-scale

0.479

High

607568

MTA1
Metastasis-associated protein MTA1

1

1

Small-scale

0.479

High

607571

STK38
Serine/threonine-protein kinase 38

1

2

Small-scale

0.479

High

607572

LRRF2
Leucine-rich repeat flightless-interacting protein 2

1

3

Small-scale

0.479

High

607583

TBK1
Serine/threonine-protein kinase TBK1

1

6

Small-scale

0.479

High

607585

HDAC6
Histone deacetylase 6

1

1

Small-scale

0.479

High

546496

INGR1
Interferon gamma receptor 1

1

0

Small-scale

0.458

High

607544

TANK
TRAF family member-associated NF-kappa-B activator

1

0

Small-scale

0.458

High

607546

NXN
Nucleoredoxin

1

0

Small-scale

0.458

High

607564

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

0

Small-scale

0.458

High

607566

ANM5
Protein arginine N-methyltransferase 5

1

0

Small-scale

0.458

High

607574

TNIP2
TNFAIP3-interacting protein 2

1

0

Small-scale

0.458

High

193566

PK3CD
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

1

4

Small-scale

0.445

High

607558

RAGE
Advanced glycosylation end product-specific receptor

1

6

Small-scale

0.445

High

607540

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.438

High

607579

TMOD3
Tropomodulin-3

1

1

Small-scale

0.437

High

421444

CSF1
Macrophage colony-stimulating factor 1

1

0

Small-scale

0.426

High

607552

IASPP
RelA-associated inhibitor

1

0

Small-scale

0.426

High

607573

LRC59
Leucine-rich repeat-containing protein 59 [Cleaved into: Leucine-rich repeat-containing protein 59, N-terminally processed]

1

3

High-throughput

0.417

High

102602

G3X8V5
ORC ubiquitin ligase 1

1

0

Small-scale

0.249

Low

607563

Q8BIS2
IF rod domain-containing protein

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024