Protein: VWF
von Willebrand factor (vWF) [Cleaved into: von Willebrand antigen 2 (von Willebrand antigen II)]

Gene: VWF
Organism: Homo sapiens
Interactions: 43
UniProt ID: P04275

Gene Ontology (top 5):
GO:0002020 - protease binding
GO:0005178 - integrin binding
GO:0005518 - collagen binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

407744

VWF
von Willebrand factor

5

7

Small-scale

0.928

High

407767

ATS13
A disintegrin and metalloproteinase with thrombospondin motifs 13

4

2

Small-scale

0.902

High

361566

FA8
Coagulation factor VIII

4

1

Small-scale

0.893

High

407749

GP1BA
Platelet glycoprotein Ib alpha chain

4

1

Small-scale

0.891

High

407745

ITB3
Integrin beta-3

2

3

Small-scale

0.768

High

399492

C4BPA
C4b-binding protein alpha chain

1

1

Small-scale

0.724

High

384080

CO1A1
Collagen alpha-1(I) chain

1

14

Small-scale

0.647

High

384274

CO3A1

1

14

Small-scale

0.647

High

407754

HGF
Hepatocyte growth factor

1

6

Small-scale

0.647

High

139676

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

2

High-throughput

0.587

High

407751

GRAB
Granzyme B

1

11

Small-scale

0.575

High

407747

PROS
Vitamin K-dependent protein S

1

6

Small-scale

0.561

High

407748

PDIA1
Protein disulfide-isomerase

1

8

Small-scale

0.561

High

407774

EGFL8
Epidermal growth factor-like protein 8

1

10

High-throughput

0.515

High

387681

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

1

5

Small-scale

0.501

High

387772

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

5

Small-scale

0.501

High

387933

FIBG
Fibrinogen gamma chain

1

5

Small-scale

0.501

High

407750

ITA2B
Integrin alpha-IIb

1

3

Small-scale

0.501

High

407757

HXA1
Homeobox protein Hox-A1

1

1

High-throughput

0.494

High

407770

OPTN
Optineurin

1

1

High-throughput

0.494

High

407773

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

3

High-throughput

0.494

High

407759

H4
Histone H4

1

0

High-throughput

0.493

High

407761

CKAP4
Cytoskeleton-associated protein 4

1

0

High-throughput

0.493

High

407764

H31T
Histone H3.1t

1

0

High-throughput

0.493

High

407763

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

High-throughput

0.489

High

407760

RAC1
Ras-related C3 botulinum toxin substrate 1

1

13

High-throughput

0.481

High

387202

APOA1
Apolipoprotein A-I

1

0

Small-scale

0.480

High

389919

ALBU
Albumin

1

0

Small-scale

0.480

High

407746

ITAV
Integrin alpha-V

1

3

Small-scale

0.479

High

407752

BIP
Endoplasmic reticulum chaperone BiP

1

9

Small-scale

0.479

High

407753

PDIA4
Protein disulfide-isomerase A4

1

8

Small-scale

0.479

High

407755

ENPL
Endoplasmin

1

3

Small-scale

0.479

High

407756

CALR
Calreticulin

1

1

Small-scale

0.479

High

407762

TP53B
TP53-binding protein 1

1

1

High-throughput

0.470

High

184679

ATX7
Ataxin-7

1

3

High-throughput

0.464

High

407769

SOCS4
Suppressor of cytokine signaling 4

1

3

High-throughput

0.439

High

407758

FXR1
RNA-binding protein FXR1

1

0

High-throughput

0.282

High

407768

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.282

High

407771

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.282

High

407765

ASCL4
Achaete-scute homolog 4

1

0

High-throughput

0.268

Low

407766

LIAT1
Protein LIAT1

1

0

High-throughput

0.268

Low

407772

Z512B
Zinc finger protein 512B

1

0

High-throughput

0.265

Low


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Last updated: 11Aug2025