HitPredict

Interactor 1: U2AF2 (P26369)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Interactor 2: TIA1 (P52912)
Cytotoxic granule associated RNA binding protein TIA1 (Nucleolysin TIA-1) (RNA-binding protein TIA-1) (T-cell-restricted intracellular antigen-1) (TIA-1)
Gene: TIA1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27160897
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0008380 - RNA splicing
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 475 Mm			1 386
+	Hs
		516364 U2AF2_HUMAN (1-475): 8.01e-89: 281: 99.79		PABP1_HUMAN (3-303): 6.45e-67: 224: 24.68
+	Hs
		680422 TIA1_HUMAN (253-467): 4.48e-34: 133: 18.61		TIA1_HUMAN (1-386): 2.53e-114: 340: 96.63
+	Hs
		516518 RBM39_HUMAN (145-471): 1.24e-48: 176: 18.23		PABP1_HUMAN (3-303): 6.45e-67: 224: 24.68
+	Hs
		516689 PABP3_HUMAN (96-421): 1.81e-46: 172: 12.12		PABP1_HUMAN (3-303): 6.45e-67: 224: 24.68
+	Hs
		641756 U2AF2_HUMAN (1-475): 8.01e-89: 281: 99.79		PABP4_HUMAN (1-97): 1.92e-20: 95.1: 21.65
+	Mm
		665745 TIA1_MOUSE (253-467): 3.18e-34: 134: 18.61		PABP1_MOUSE (3-303): 7.54e-67: 224: 24.68
+	Hs
		516471 TIAR_HUMAN (256-464): 3.55e-30: 122: 15.79		PABP1_HUMAN (3-303): 6.45e-67: 224: 24.68
+	Hs
		516730 PUF60_HUMAN (92-474): 3.07e-22: 101: 20.67		PABP1_HUMAN (3-303): 6.45e-67: 224: 24.68
+	Hs
		516339 PABP1_HUMAN (4-260): 2.21e-19: 93.1: 14.93		PABP1_HUMAN (3-303): 6.45e-67: 224: 24.68
+	Sc
		376694 PABP_YEAST (85-401): 2.06e-44: 165: 13.13		PUB1_YEAST (7-185): 3.03e-31: 125: 40.56
+	Hs
		1031328 RBM39_HUMAN (145-471): 1.24e-48: 176: 18.23		PABP4_HUMAN (1-97): 1.92e-20: 95.1: 21.65
+	Hs
		680439 TIA1_HUMAN (253-467): 4.48e-34: 133: 18.61		TIAR_HUMAN (98-295): 6.66e-36: 136: 24.02
+	Hs
		963504 TIAR_HUMAN (256-464): 3.55e-30: 122: 15.79		TIAR_HUMAN (98-295): 6.66e-36: 136: 24.02
+	Sc
		376562 PABP_YEAST (85-401): 2.06e-44: 165: 13.13		PABP_YEAST (1-103): 2.01e-18: 88.9: 19.23
+	Zm
		8143 A0A1D6ELH4_MAIZE (87-430): 1.53e-45: 170: 13.33		A0A1D6ELH4_MAIZE (211-294): 5.43e-11: 66.2: 20.00
+	Hs
		474021 PAB4L_HUMAN (250-474): 7.87e-32: 127: 12.00		PABP4_HUMAN (1-97): 1.92e-20: 95.1: 21.65
+	Hs
		1031490 PUF60_HUMAN (92-474): 3.07e-22: 101: 20.67		PABP4_HUMAN (1-97): 1.92e-20: 95.1: 21.65
+	Zm
		111724 K7TYT2_MAIZE (229-466): 2.03e-29: 121: 15.55		K7TYT2_MAIZE (186-284): 3.03e-13: 72.7: 20.79