HitPredict

Interactor 1: SAHH2 (O43865)
S-adenosylhomocysteine hydrolase-like protein 1 (DC-expressed AHCY-like molecule) (IP(3)Rs binding protein released with IP(3)) (IRBIT) (Putative adenosylhomocysteinase 2) (S-adenosyl-L-homocysteine hydrolase 2) (AdoHcyase 2)
Gene: AHCYL1

Interactor 2: SRPK1 (Q96SB4)
SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)
Gene: SRPK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.53	0.60	0.569

Property	Details
Experiments	23602568
Identification Methods	enzymatic study, protein kinase assay
Interaction Type	direct interaction, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 655
+	Hs
		216490 SAHH2_HUMAN (1-530): 0: 909: 100.00		SRPK2_HUMAN (48-655): 9.43e-136: 415: 57.97
+	Hs
		216511 SAHH2_HUMAN (1-530): 0: 909: 100.00		KS6A2_HUMAN (1-374): 1.21e-78: 266: 14.00
+	Hs
		1071678 SAHH3_HUMAN (7-530): 0: 879: 86.43		KS6A2_HUMAN (1-374): 1.21e-78: 266: 14.00
+	Hs
		216586 SAHH2_HUMAN (1-530): 0: 909: 100.00		CLK4_HUMAN (436-654): 5.51e-63: 218: 23.89
+	Hs
		216472 SAHH2_HUMAN (1-530): 0: 909: 100.00		CLK3_HUMAN (484-653): 1.02e-60: 216: 28.65
+	Hs
		216471 SAHH2_HUMAN (1-530): 0: 909: 100.00		CLK1_HUMAN (436-654): 8.6e-61: 212: 23.45
+	Hs
		1293646 SAHH3_HUMAN (7-530): 0: 879: 86.43		CLK4_HUMAN (436-654): 5.51e-63: 218: 23.89
+	Hs
		834102 SAHH3_HUMAN (7-530): 0: 879: 86.43		CLK3_HUMAN (484-653): 1.02e-60: 216: 28.65
+	Hs
		833796 SAHH3_HUMAN (7-530): 0: 879: 86.43		CLK1_HUMAN (436-654): 8.6e-61: 212: 23.45
+	Hs
		617804 SAHH_HUMAN (105-530): 0: 727: 50.82		CDK2_HUMAN (414-653): 1.01e-65: 219: 19.43