Protein: PRDM5
PR domain zinc finger protein 5 (EC 2.1.1.-) (PR domain-containing protein 5)

Gene: PRDM5
Organism: Homo sapiens
Interactions: 57
UniProt ID: Q9NQX1

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000278 - mitotic cell cycle
GO:0000976 - transcription cis-regulatory region binding
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

841473

RBM34
RNA-binding protein 34

2

1

High-throughput

0.811

High

1323541

ZN687
Zinc finger protein 687

2

2

High-throughput

0.811

High

1395486

ZFP91
E3 ubiquitin-protein ligase ZFP91

2

14

High-throughput

0.811

High

1447291

PRD10
PR domain zinc finger protein 10

2

3

High-throughput

0.811

High

1447538

RBM28
RNA-binding protein 28

2

1

High-throughput

0.811

High

1447541

ZBTB4
Zinc finger and BTB domain-containing protein 4

2

5

High-throughput

0.811

High

1406403

GFI1
Zinc finger protein Gfi-1

2

12

Small-scale

0.781

High

600205

ZNF22
Zinc finger protein 22

1

13

High-throughput

0.691

High

1333145

ZFP62
Zinc finger protein 62 homolog

1

1

High-throughput

0.691

High

1430781

GZF1
GDNF-inducible zinc finger protein 1

1

11

High-throughput

0.691

High

290750

SURF6
Surfeit locus protein 6

2

3

High-throughput

0.628

High

355602

NSD2
Histone-lysine N-methyltransferase NSD2

2

1

High-throughput

0.628

High

1193390

GLYR1
Cytokine-like nuclear factor N-PAC

2

1

High-throughput

0.628

High

1314249

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

2

1

High-throughput

0.628

High

1351480

BRX1
Ribosome biogenesis protein BRX1 homolog

2

4

High-throughput

0.628

High

1447543

ABT1
Activator of basal transcription 1

2

2

High-throughput

0.628

High

1447546

YBOX2
Y-box-binding protein 2

2

8

High-throughput

0.628

High

714654

TYK2
Non-receptor tyrosine-protein kinase TYK2

2

3

High-throughput

0.606

High

1447545

RASD1
Dexamethasone-induced Ras-related protein 1

2

1

High-throughput

0.606

High

183520

CASC3
Protein CASC3

2

0

High-throughput

0.602

High

190170

TNC18
Trinucleotide repeat-containing gene 18 protein

2

0

High-throughput

0.602

High

451707

PGK2
Phosphoglycerate kinase 2

2

0

High-throughput

0.602

High

1293821

FBX11
F-box only protein 11

2

0

High-throughput

0.602

High

1389080

THA11
THAP domain-containing protein 11

2

0

High-throughput

0.602

High

1408144

BAG1
BAG family molecular chaperone regulator 1

2

0

High-throughput

0.602

High

1239791

FAP20
Fanconi anemia core complex-associated protein 20

2

0

High-throughput

0.580

High

1447539

ADPRS
ADP-ribosylhydrolase ARH3

2

0

High-throughput

0.580

High

1447544

RL26L
Ribosomal protein uL24-like

2

2

High-throughput

0.558

High

1110110

HDAC1
Histone deacetylase 1

1

2

Small-scale

0.554

High

733083

VIPR1
Vasoactive intestinal polypeptide receptor 1

2

1

High-throughput

0.553

High

528360

THIO
Thioredoxin

1

1

High-throughput

0.536

High

785476

RL4
Large ribosomal subunit protein uL4

1

3

High-throughput

0.536

High

975970

RL7A
Large ribosomal subunit protein eL8

1

2

High-throughput

0.536

High

985353

RL10A
Large ribosomal subunit protein uL1

1

4

High-throughput

0.536

High

1148169

PUM3
Pumilio homolog 3

1

1

High-throughput

0.536

High

1307327

H2A2B
Histone H2A type 2-B

1

1

High-throughput

0.536

High

1429909

SP130
Histone deacetylase complex subunit SAP130

1

1

High-throughput

0.536

High

1447547

RL36
Large ribosomal subunit protein eL36

1

9

High-throughput

0.536

High

1396309

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

0

Small-scale

0.530

High

986236

RL8
Large ribosomal subunit protein uL2

1

0

High-throughput

0.513

High

1339561

NEUA
N-acylneuraminate cytidylyltransferase

1

0

High-throughput

0.513

High

1370127

RENT1
Regulator of nonsense transcripts 1

1

0

High-throughput

0.513

High

1435602

RPF2
Ribosome production factor 2 homolog

1

0

High-throughput

0.513

High

1446256

NGRN
Neugrin

1

0

High-throughput

0.513

High

1447540

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

0

High-throughput

0.513

High

230574

KIF1C
Kinesin-like protein KIF1C

1

1

High-throughput

0.489

High

404456

GCR
Glucocorticoid receptor

1

14

High-throughput

0.479

High

1447542

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

8

High-throughput

0.479

High

1032053

TFAP4
Transcription factor AP-4

1

0

High-throughput

0.458

High

1214623

EEIG2
EEIG family member 2

2

0

High-throughput

0.328

High

1411049

CCD77
Coiled-coil domain-containing protein 77

2

0

High-throughput

0.328

High

771957

CLCN1
Chloride channel protein 1

2

0

High-throughput

0.316

High

1433875

FBX44
F-box only protein 44

2

0

High-throughput

0.316

High

457993

TRY1
Serine protease 1

1

0

High-throughput

0.279

Low

1037660

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.279

Low

1355935

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

1

0

High-throughput

0.279

Low

1435564

SH24A
SH2 domain-containing protein 4A

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025