HitPredict

Interactor 1: CREB3 (O43889)
Cyclic AMP-responsive element-binding protein 3 (CREB-3) (cAMP-responsive element-binding protein 3) (Leucine zipper protein) (Luman) (Transcription factor LZIP-alpha) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3 (N-terminal Luman) (Transcriptionally active form)]
Gene: CREB3

Interactor 2: IBP5 (P24593)
Insulin-like growth factor-binding protein 5 (IBP-5) (IGF-binding protein 5) (IGFBP-5)
Gene: IGFBP5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	25910212, 31515488
Identification Methods	two hybrid, two hybrid bait and prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001558 - regulation of cell growth
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 371 Hs			1 272
+	Hs
		216814 CREB3_HUMAN (1-371): 1.33e-118: 350: 100.00		TICN3_HUMAN (154-268): 2.71e-25: 105: 23.28
+	Hs
		996138 CR3L1_HUMAN (23-327): 3.61e-45: 164: 27.17		TICN1_HUMAN (129-264): 1.37e-24: 103: 20.98