HitPredict

Interactor 1: NR1I2 (O54915)
Nuclear receptor subfamily 1 group I member 2 (Orphan nuclear receptor PXR) (Pregnane X receptor)
Gene: NR1I2

Interactor 2: RXRG (P28705)
Retinoic acid receptor RXR-gamma (Nuclear receptor subfamily 2 group B member 3) (Retinoid X receptor gamma)
Gene: RXRG

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 20211142
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Hormone_recep~Hormone_recep, Hormone_recep~zf-C4, zf-C4~zf-C4
Common GO terms GO:0004879 - nuclear receptor activity
GO:0008270 - zinc ion binding
GO:0030154 - cell differentiation
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 431
Mm

1 463
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024