Interactor 1: SOCS5 (O54928)
Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2-containing protein 5)
Gene: SOCS5
Interactor 2: JAK2 (Q62120)
Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)
Gene: JAK2
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23990909 |
| Identification Methods | pull down |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FERM_F1~SH2, PK_Tyr_Ser-Thr~SH2, SH2~SH2, SH2~SOCS_box |
| Common GO terms | GO:0005737 - cytoplasm GO:0007259 - cell surface receptor signaling pathway via JAK-STAT GO:0019221 - cytokine-mediated signaling pathway GO:0035556 - intracellular signal transduction |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
