Protein: RLMKL
Ribosomal RNA large subunit methyltransferase K/L [Includes: 23S rRNA m2G2445 methyltransferase (EC 2.1.1.173) (rRNA (guanine-N(2)-)-methyltransferase RlmL); 23S rRNA m7G2069 methyltransferase (EC 2.1.1.264) (rRNA (guanine-N(7)-)-methyltransferase RlmK)]

Gene: RLMKL, rlmL
Organism: Escherichia coli K-12
Interactions: 51
UniProt ID: P75864

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005737 - cytoplasm
GO:0008990 - rRNA (guanine-N2-)-methyltransferase activity
GO:0031167 - rRNA methylation
GO:0052915 - 23S rRNA (guanine(2445)-N(2))-methyltransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

460843

RL1
Large ribosomal subunit protein uL1

3

1

High-throughput

0.657

High

741825

RLUB
Ribosomal large subunit pseudouridine synthase B

2

3

High-throughput

0.640

High

464319

CSPD
Cold shock-like protein CspD

2

3

High-throughput

0.588

High

465440

CSPA
Cold shock protein CspA

2

3

High-throughput

0.588

High

621070

PSS
CDP-diacylglycerol--serine O-phosphatidyltransferase

2

0

High-throughput

0.585

High

739453

RLMN
Dual-specificity RNA methyltransferase RlmN

2

0

High-throughput

0.585

High

460006

RPPH
RNA pyrophosphohydrolase

2

0

High-throughput

0.563

High

466055

YBCJ
Putative RNA-binding protein YbcJ

2

0

High-throughput

0.563

High

465701

RLUC
Ribosomal large subunit pseudouridine synthase C

1

3

High-throughput

0.561

High

462042

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.536

High

465724

RSUA
Ribosomal small subunit pseudouridine synthase A

1

3

High-throughput

0.536

High

599061

RNR
Ribonuclease R

1

1

High-throughput

0.536

High

889978

RL2
Large ribosomal subunit protein uL2

1

1

High-throughput

0.536

High

888484

RAPA
RNA polymerase-associated protein RapA

1

0

High-throughput

0.518

High

357129

RS7
Small ribosomal subunit protein uS7

1

0

High-throughput

0.513

High

462242

RS4
Small ribosomal subunit protein uS4

1

0

High-throughput

0.513

High

462557

RS9
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

469260

RL17
Large ribosomal subunit protein bL17

1

0

High-throughput

0.513

High

597039

CATE
Catalase HPII

1

0

High-throughput

0.513

High

599108

RNE
Ribonuclease E

1

0

High-throughput

0.513

High

599889

LPXD
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase

1

0

High-throughput

0.513

High

890036

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.513

High

940067

LSRK
Autoinducer-2 kinase

1

0

High-throughput

0.513

High

599090

SRMB
ATP-dependent RNA helicase SrmB

1

1

High-throughput

0.489

High

464355

CSPE
Cold shock-like protein CspE

1

3

High-throughput

0.484

High

465492

CSPC
Cold shock-like protein CspC

1

3

High-throughput

0.484

High

458962

HFQ
RNA-binding protein Hfq

1

0

High-throughput

0.464

High

462949

TGT
Queuine tRNA-ribosyltransferase

1

0

High-throughput

0.464

High

469672

YFIF
Uncharacterized tRNA/rRNA methyltransferase YfiF

1

0

High-throughput

0.464

High

466365

PCNB
Poly(A) polymerase I

1

0

High-throughput

0.458

High

463643

YEEX
UPF0265 protein YeeX

1

1

High-throughput

0.437

High

343469

MANA
Mannose-6-phosphate isomerase

2

0

High-throughput

0.322

High

463502

TRMB
tRNA

2

0

High-throughput

0.307

High

466782

FLIG
Flagellar motor switch protein FliG

1

0

High-throughput

0.282

High

393710

APPY
HTH-type transcriptional regulator AppY

1

0

High-throughput

0.279

Low

466519

NAPC
Cytochrome c-type protein NapC

1

0

High-throughput

0.279

Low

467553

YEBG
Uncharacterized protein YebG

1

0

High-throughput

0.279

Low

579039

NADE
NH(3)-dependent NAD(+) synthetase

1

0

High-throughput

0.279

Low

621873

FDNG
Formate dehydrogenase, nitrate-inducible, major subunit

1

0

High-throughput

0.279

Low

676799

3PASE
Inorganic triphosphatase

1

0

High-throughput

0.279

Low

940065

YNBC
Uncharacterized protein YnbC

1

0

High-throughput

0.279

Low

940066

YFGI
Uncharacterized protein YfgI

1

0

High-throughput

0.279

Low

940068

MOCA
Molybdenum cofactor cytidylyltransferase

1

0

High-throughput

0.279

Low

484898

BIPA
Large ribosomal subunit assembly factor BipA

1

0

High-throughput

0.276

Low

462632

RNPA
Ribonuclease P protein component

1

0

High-throughput

0.253

Low

463462

YIHI
Der GTPase-activating protein YihI

1

0

High-throughput

0.253

Low

464791

PHOL
PhoH-like protein

1

0

High-throughput

0.253

Low

465172

DEAD
ATP-dependent RNA helicase DeaD

1

0

High-throughput

0.253

Low

468360

FABI
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI

1

0

High-throughput

0.253

Low

469161

SPOT
Bifunctional

1

0

High-throughput

0.249

Low

936112

CSRA
Carbon storage regulator

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024