HitPredict

Interactor 1: PER2 (O54943)
Period circadian protein homolog 2 (mPER2) (Circadian clock protein PERIOD 2)
Gene: PER2

Interactor 2: CRY1 (P97784)
Cryptochrome-1
Gene: CRY1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 14701732, 23418588, 21680841, 25127877, 22170608, 24737000, 24413057, 23079727, 24855952, 23555304, 23452855
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid, anti bait coimmunoprecipitation, tandem affinity purification, x-ray crystallography, pull down, isothermal titration calorimetry, comigration in non denaturing gel electrophoresis, biophysical and 2 others

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Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_photolyase~Period_C, FAD_binding_7~Period_C
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 12 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1257
Mm

1 606
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Last updated: 15 Jul 2024