HitPredict

Interactor 1: ACK1 (O54967)
Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2)
Gene: Tnk2

Interactor 2: ARVC (P98203)
Splicing regulator ARVCF (Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog)
Gene: Arvcf

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29254152
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0005912 - adherens junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1055 Mm			1 962
+	Hs
		239025 YES_HUMAN (1-400): 5.47e-131: 410: 30.18		CTND1_HUMAN (1-929): 0: 674: 46.38
+	Hs
		239024 FYN_HUMAN (1-400): 2.25e-129: 405: 30.94		CTND1_HUMAN (1-929): 0: 674: 46.38
+	Hs
		239093 EPHA4_HUMAN (74-487): 1.22e-123: 404: 24.82		CTND1_HUMAN (1-929): 0: 674: 46.38
+	Hs
		239023 LCK_HUMAN (1-398): 3.4e-128: 401: 30.33		CTND1_HUMAN (1-929): 0: 674: 46.38
+	Hs
		239035 SRC_HUMAN (1-400): 1.7e-127: 400: 31.42		CTND1_HUMAN (1-929): 0: 674: 46.38
+	Mm
		193579 ACK1_MOUSE (1-1055): 0: 865: 100.00		CTND2_MOUSE (2-373): 1.27e-17: 90.6: 15.75
+	Mm
		222850 ACK1_MOUSE (1-1055): 0: 865: 100.00		PKP4_MOUSE (3-330): 6.48e-14: 78.6: 14.84
+	Hs
		872698 EPHA4_HUMAN (74-487): 1.22e-123: 404: 24.82		PKP2_HUMAN (43-861): 5.13e-144: 452: 24.03
+	Hs
		411837 LCK_HUMAN (1-398): 3.4e-128: 401: 30.33		PKP2_HUMAN (43-861): 5.13e-144: 452: 24.03
+	Hs
		542198 EPHB2_HUMAN (4-506): 2.6e-126: 413: 23.00		PLAK_HUMAN (193-827): 5.71e-95: 318: 17.94
+	Hs
		542244 EPHA4_HUMAN (74-487): 1.22e-123: 404: 24.82		PLAK_HUMAN (193-827): 5.71e-95: 318: 17.94
+	Hs
		411579 LCK_HUMAN (1-398): 3.4e-128: 401: 30.33		PLAK_HUMAN (193-827): 5.71e-95: 318: 17.94
+	Hs
		337371 ABL1_HUMAN (2-994): 5.34e-148: 472: 20.16		CTNB1_HUMAN (581-947): 3.44e-11: 69.4: 13.72
+	Hs
		626107 FAK1_HUMAN (6-718): 6.3e-131: 425: 21.35		APC_HUMAN (376-583): 4.15e-11: 69.5: 24.19
+	Hs
		665553 EPHB2_HUMAN (4-506): 2.6e-126: 413: 23.00		CTNB1_HUMAN (581-947): 3.44e-11: 69.4: 13.72
+	Hs
		872696 EPHA4_HUMAN (74-487): 1.22e-123: 404: 24.82		PKP4_HUMAN (3-348): 3.18e-12: 72.8: 14.61
+	Hs
		412054 FYN_HUMAN (1-400): 2.25e-129: 405: 30.94		CTNB1_HUMAN (581-947): 3.44e-11: 69.4: 13.72
+	Hs
		411829 LCK_HUMAN (1-398): 3.4e-128: 401: 30.33		PKP4_HUMAN (3-348): 3.18e-12: 72.8: 14.61
+	At
		1320990 PBS1_ARATH (35-474): 2.35e-126: 394: 19.70		PUB10_ARATH (434-787): 1.87e-13: 76.3: 14.80
+	Hs
		522819 SRC_HUMAN (1-400): 1.7e-127: 400: 31.42		CTNB1_HUMAN (581-947): 3.44e-11: 69.4: 13.72