HitPredict

Interactor 1: NCK2 (O55033)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: PHAG1 (Q3U1F9)
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane phosphoprotein Cbp)
Gene: Pag1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	26512138
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PAG~SH2
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 380 Mm			1 429
+	Mm
		1112224 NCK1_MOUSE (1-379): 6.37e-88: 272: 67.19		PHAG1_MOUSE (1-429): 0: 785: 100.00
+	Mm
		643088 P85A_MOUSE (24-379): 1.32e-31: 128: 12.57		PHAG1_MOUSE (1-429): 0: 785: 100.00
+	Mm
		763390 FYN_MOUSE (7-205): 4.71e-22: 99.5: 12.68		PHAG1_MOUSE (1-429): 0: 785: 100.00
+	Mm
		1112191 GRB2_MOUSE (1-60): 1.6e-16: 79.5: 29.51		PHAG1_MOUSE (1-429): 0: 785: 100.00
+	Mm
		782848 CSK_MOUSE (2-121): 3.39e-13: 72.6: 14.84		PHAG1_MOUSE (1-429): 0: 785: 100.00
+	Rn
		693647 CSK_RAT (2-121): 3.39e-13: 72.6: 14.84		PHAG1_RAT (1-429): 0: 764: 89.51
+	Hs
		412375 FYN_HUMAN (7-205): 4.93e-22: 99.5: 12.68		PHAG1_HUMAN (1-429): 0: 705: 78.21
+	Hs
		523175 SRC_HUMAN (7-120): 5.83e-16: 81.3: 18.10		PHAG1_HUMAN (1-429): 0: 705: 78.21
+	Hs
		924899 GRB2_HUMAN (3-60): 3.75e-16: 78.7: 31.03		PHAG1_HUMAN (1-429): 0: 705: 78.21