Interactor 1: AT2A2 (O55143)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
Gene: Atp2a2
Interactor 2: PPLA (P61014)
Cardiac phospholamban (PLB)
Gene: Pln
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.64 | 1.00 | 0.805 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15201433, 31046837, unassigned1853 |
| Identification Methods | affinity chromatography technology, anti bait coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cation_ATPase_C~Phospholamban |
| Common GO terms | GO:0002026 - regulation of the force of heart contraction GO:0006816 - calcium ion transport GO:0006874 - intracellular calcium ion homeostasis GO:0016020 - membrane GO:0016529 - sarcoplasmic reticulum and 3 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
