Interactor 1: BUB3 (O43684)
Mitotic checkpoint protein BUB3
Gene: BUB3

Interactor 2: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 29764989
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000776 - kinetochore
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0007094 - mitotic spindle assembly checkpoint signaling
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 328
Hs

1 603
+ Hs
+ Hs
+ Hs
+ Hs
+ Zm
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025