HitPredict

Interactor 1: HTSF1 (O43719)
17S U2 SnRNP complex component HTATSF1 (HIV Tat-specific factor 1) (Tat-SF1)
Gene: HTATSF1

Interactor 2: HDAC6 (Q9UBN7)
Protein deacetylase HDAC6 (EC 3.5.1.-) (E3 ubiquitin-protein ligase HDAC6) (EC 2.3.2.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-)
Gene: HDAC6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	21220424
Identification Methods	affinity chromatography technology, two hybrid, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 755 Hs			1 1215
+	Hs
		1102122 PABP4_HUMAN (62-285): 8.61e-31: 130: 12.66		HDAC6_HUMAN (1-1215): 0: 1440: 100.00
+	Hs
		550501 PABP1_HUMAN (62-264): 1.45e-29: 126: 12.14		HDAC6_HUMAN (1-1215): 0: 1440: 100.00
+	Hs
		1152666 ELAV1_HUMAN (133-400): 1.43e-29: 122: 15.00		HDAC6_HUMAN (1-1215): 0: 1440: 100.00
+	Hs
		1033284 EWS_HUMAN (126-217): 8.4e-16: 83.3: 26.60		HDAC6_HUMAN (1-1215): 0: 1440: 100.00
+	Hs
		775354 FUS_HUMAN (110-216): 7.18e-11: 67.5: 24.07		HDAC6_HUMAN (1-1215): 0: 1440: 100.00
+	Mm
		1223271 ELAV4_MOUSE (88-421): 9.59e-36: 141: 13.16		HDAC4_MOUSE (424-873): 9.92e-152: 485: 37.16
+	Mm
		1221946 ELAV2_MOUSE (117-381): 1.2e-34: 137: 15.13		HDAC4_MOUSE (424-873): 9.92e-152: 485: 37.16
+	Hs
		1102041 PABP4_HUMAN (62-285): 8.61e-31: 130: 12.66		HDAC2_HUMAN (78-489): 3.62e-158: 483: 20.74
+	Hs
		550390 PABP1_HUMAN (62-264): 1.45e-29: 126: 12.14		HDAC2_HUMAN (78-489): 3.62e-158: 483: 20.74
+	Mm
		1000302 ELAV1_MOUSE (119-400): 3.38e-30: 123: 13.95		HDAC4_MOUSE (424-873): 9.92e-152: 485: 37.16
+	Hs
		550528 PABP1_HUMAN (62-264): 1.45e-29: 126: 12.14		HDAC5_HUMAN (33-471): 8.24e-146: 471: 32.48
+	Hs
		940976 ELAV1_HUMAN (133-400): 1.43e-29: 122: 15.00		HDAC4_HUMAN (405-873): 3.54e-147: 473: 36.51
+	Sc
		403415 PABP_YEAST (62-422): 1.05e-25: 114: 13.46		RPD3_YEAST (83-473): 6.21e-150: 459: 20.63
+	Mm
		1222933 EWS_MOUSE (126-217): 4.98e-16: 84.1: 26.60		HDA10_MOUSE (85-483): 1.09e-157: 488: 49.13
+	Hs
		1033104 EWS_HUMAN (126-217): 8.4e-16: 83.3: 26.60		HDAC2_HUMAN (78-489): 3.62e-158: 483: 20.74
+	Hs
		775234 FUS_HUMAN (110-216): 7.18e-11: 67.5: 24.07		HDAC2_HUMAN (78-489): 3.62e-158: 483: 20.74
+	Hs
		188244 EWS_HUMAN (126-217): 8.4e-16: 83.3: 26.60		HDAC3_HUMAN (479-890): 1.13e-146: 450: 18.29