HitPredict

Interactor 1: MED14 (O60244)
Mediator of RNA polymerase II transcription subunit 14 (Activator-recruited cofactor 150 kDa component) (ARC150) (Cofactor required for Sp1 transcriptional activation subunit 2) (CRSP complex subunit 2) (Mediator complex subunit 14) (RGR1 homolog) (hRGR1) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150)
Gene: MED14

Interactor 2: RPAB1 (P19388)
DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RNA polymerases I, II, and III subunit ABC1) (DNA-directed RNA polymerase II 23 kDa polypeptide) (DNA-directed RNA polymerase II subunit E) (RPB5 homolog) (XAP4)
Gene: POLR2E

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	24981860, 35271311
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1454 Hs			1 210
+	Sc
		581332 MED14_YEAST (2-463): 8.6e-138: 453: 18.45		RPAB1_YEAST (2-208): 1.31e-77: 233: 43.66
+	Hs
		123850 SPT5H_HUMAN (1062-1272): 9.25e-11: 68.8: 14.41		RPAB1_HUMAN (1-210): 1.63e-101: 293: 100.00
+	Bt
		102291 RPB1_BOVIN (1059-1159): 8.45e-09: 62.5: 23.30		RPAB1_BOVIN (1-210): 6.21e-102: 295: 98.57
+	Hs
		583647 RPB1_HUMAN (1059-1159): 8.88e-09: 62.5: 23.30		RPAB1_HUMAN (1-210): 1.63e-101: 293: 100.00