HitPredict

Interactor 1: PCDH7 (O60245)
Protocadherin-7 (Brain-heart protocadherin) (BH-Pcdh)
Gene: PCDH7

Interactor 2: RYK (P34925)
Tyrosine-protein kinase RYK (EC 2.7.10.1)
Gene: RYK

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	33961781, 35384245, 21875946
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1069 Hs			1 607
+	Hs
		225492 PCDH7_HUMAN (1-1069): 0: 909: 100.00		FGFR1_HUMAN (137-599): 4.53e-145: 441: 27.29
+	Hs
		225521 PCDH7_HUMAN (1-1069): 0: 909: 100.00		FGFR4_HUMAN (137-604): 9.44e-129: 398: 26.10
+	Hs
		225482 PCDH7_HUMAN (1-1069): 0: 909: 100.00		MET_HUMAN (265-593): 1.87e-59: 217: 35.95
+	Hs
		713881 CELR3_HUMAN (2-839): 0: 651: 23.34		RYK_HUMAN (1-607): 1.73e-146: 438: 100.00
+	Hs
		713898 PCDG6_HUMAN (230-915): 2.09e-159: 497: 27.17		RYK_HUMAN (1-607): 1.73e-146: 438: 100.00
+	Hs
		713880 CELR1_HUMAN (423-1064): 2.58e-135: 455: 21.75		RYK_HUMAN (1-607): 1.73e-146: 438: 100.00
+	Hs
		713873 CELR2_HUMAN (527-1068): 9.01e-123: 418: 22.58		RYK_HUMAN (1-607): 1.73e-146: 438: 100.00
+	Hs
		713840 PCD20_HUMAN (26-903): 1.05e-118: 390: 31.92		RYK_HUMAN (1-607): 1.73e-146: 438: 100.00
+	Hs
		713825 FAT4_HUMAN (425-1064): 4.05e-113: 389: 20.64		RYK_HUMAN (1-607): 1.73e-146: 438: 100.00
+	Hs
		508294 PCDB7_HUMAN (317-876): 3.84e-118: 384: 26.80		FGFR1_HUMAN (137-599): 4.53e-145: 441: 27.29
+	Hs
		523158 CELR2_HUMAN (527-1068): 9.01e-123: 418: 22.58		SRC_HUMAN (315-602): 2.06e-108: 338: 30.80
+	Hs
		713899 PCDG5_HUMAN (3-527): 1.35e-89: 310: 20.86		RYK_HUMAN (1-607): 1.73e-146: 438: 100.00
+	Hs
		713790 PCDH1_HUMAN (2-526): 1.42e-88: 309: 17.51		RYK_HUMAN (1-607): 1.73e-146: 438: 100.00
+	Hs
		713897 PCDG7_HUMAN (3-527): 7.62e-89: 308: 21.38		RYK_HUMAN (1-607): 1.73e-146: 438: 100.00
+	Hs
		713862 PCD16_HUMAN (542-1064): 1.05e-84: 304: 20.11		RYK_HUMAN (1-607): 1.73e-146: 438: 100.00
+	Hs
		523068 PCD20_HUMAN (26-903): 1.05e-118: 390: 31.92		SRC_HUMAN (315-602): 2.06e-108: 338: 30.80
+	Mm
		555033 PCDAA_MOUSE (242-865): 5.05e-150: 473: 26.68		MET_MOUSE (330-593): 4.01e-59: 216: 39.47
+	Hs
		713894 PCDB2_HUMAN (285-844): 3.21e-62: 229: 32.47		RYK_HUMAN (1-607): 1.73e-146: 438: 100.00
+	Hs
		523229 PCDG5_HUMAN (3-527): 1.35e-89: 310: 20.86		SRC_HUMAN (315-602): 2.06e-108: 338: 30.80
+	Mm
		555050 CELR2_MOUSE (527-1068): 4.06e-123: 419: 22.58		MET_MOUSE (330-593): 4.01e-59: 216: 39.47