HitPredict

Interactor 1: KLK8 (O60259)
Kallikrein-8 (hK8) (EC 3.4.21.118) (Neuropsin) (NP) (Ovasin) (Serine protease 19) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein)
Gene: KLK8

Interactor 2: ATP4A (P20648)
Potassium-transporting ATPase alpha chain 1 (EC 7.2.2.19) (Gastric H(+)/K(+) ATPase subunit alpha) (Proton pump)
Gene: ATP4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 260 Hs			1 1035
+	Hs
		531010 KLK5_HUMAN (24-259): 1.95e-97: 288: 47.48		AT1A3_HUMAN (37-1035): 0: 1014: 65.37
+	Mm
		372264 CFAD_MOUSE (15-255): 5.96e-45: 153: 38.65		AT1A1_MOUSE (14-1035): 0: 1029: 62.21
+	Hs
		530827 GRAH_HUMAN (28-256): 4.11e-43: 148: 37.29		AT1A3_HUMAN (37-1035): 0: 1014: 65.37
+	Hs
		595525 GRAH_HUMAN (28-256): 4.11e-43: 148: 37.29		AT12A_HUMAN (8-1035): 0: 944: 64.28
+	Hs
		561693 TMPS4_HUMAN (6-259): 1.55e-93: 283: 31.46		AT2A2_HUMAN (53-1024): 0: 777: 26.83
+	Mm
		223145 CFAD_MOUSE (15-255): 5.96e-45: 153: 38.65		AT2A2_MOUSE (53-1024): 0: 776: 26.83