HitPredict

Interactor 1: KLK8 (O60259)
Kallikrein-8 (hK8) (EC 3.4.21.118) (Neuropsin) (NP) (Ovasin) (Serine protease 19) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein)
Gene: KLK8

Interactor 2: ORNT1 (Q9Y619)
Mitochondrial ornithine transporter 1 (Solute carrier family 25 member 15)
Gene: SLC25A15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 260 Hs			1 301
+	Hs
		420764 KLK1_HUMAN (12-259): 3.93e-106: 309: 41.09		ORNT1_HUMAN (1-301): 2.06e-90: 272: 100.00
+	Hs
		225952 KLK8_HUMAN (1-260): 8.28e-126: 359: 100.00		ADT1_HUMAN (100-301): 8.49e-40: 142: 20.57
+	Hs
		420735 KLK1_HUMAN (12-259): 3.93e-106: 309: 41.09		ADT1_HUMAN (100-301): 8.49e-40: 142: 20.57
+	Hs
		518440 KLK6_HUMAN (10-259): 4.17e-102: 298: 45.42		ADT3_HUMAN (101-301): 6.41e-39: 140: 20.67
+	Hs
		518527 KLK9_HUMAN (30-258): 4.99e-100: 293: 48.05		ADT3_HUMAN (101-301): 6.41e-39: 140: 20.67
+	Mm
		372690 CFAD_MOUSE (15-255): 5.96e-45: 153: 38.65		ORNT1_MOUSE (1-301): 2.77e-91: 275: 95.02
+	Hs
		1345088 TMPS4_HUMAN (6-259): 1.55e-93: 283: 31.46		S2513_HUMAN (109-297): 1.32e-37: 143: 24.34
+	Hs
		518209 TMPS4_HUMAN (6-259): 1.55e-93: 283: 31.46		ADT1_HUMAN (100-301): 8.49e-40: 142: 20.57
+	Hs
		518291 KLK7_HUMAN (28-258): 8.8e-97: 285: 46.98		ADT3_HUMAN (101-301): 6.41e-39: 140: 20.67
+	Hs
		198386 KLK10_HUMAN (36-259): 5.58e-92: 274: 45.85		ADT3_HUMAN (101-301): 6.41e-39: 140: 20.67
+	Hs
		213763 KLK1_HUMAN (12-259): 3.93e-106: 309: 41.09		MCAT_HUMAN (206-299): 1.05e-17: 83.3: 28.28
+	Hs
		213774 KLK15_HUMAN (23-259): 7.94e-100: 293: 45.57		MCAT_HUMAN (206-299): 1.05e-17: 83.3: 28.28
+	Hs
		1154119 KLK5_HUMAN (24-259): 1.95e-97: 288: 47.48		SCMC2_HUMAN (209-299): 2.62e-17: 83.7: 21.98
+	Mm
		372108 CFAD_MOUSE (15-255): 5.96e-45: 153: 38.65		SCMC1_MOUSE (94-298): 1.61e-45: 161: 18.05
+	Mm
		372079 CFAD_MOUSE (15-255): 5.96e-45: 153: 38.65		S2512_MOUSE (109-298): 1.36e-39: 148: 24.21
+	Mm
		371634 CFAD_MOUSE (15-255): 5.96e-45: 153: 38.65		ADT1_MOUSE (100-301): 3.45e-40: 143: 20.57
+	Mm
		371643 CFAD_MOUSE (15-255): 5.96e-45: 153: 38.65		ADT2_MOUSE (101-301): 1.69e-39: 141: 20.67
+	Mm
		372718 CFAD_MOUSE (15-255): 5.96e-45: 153: 38.65		MCAT_MOUSE (206-299): 2.69e-18: 84.8: 28.28