HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: ABCB7 (O75027)
Iron-sulfur clusters transporter ABCB7, mitochondrial (ATP-binding cassette sub-family B member 7, mitochondrial) (ATP-binding cassette transporter 7) (ABC transporter 7 protein)
Gene: ABCB7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 752
+	Hs
		228813 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ABCBA_HUMAN (136-709): 1.19e-158: 479: 26.60
+	Hs
		226140 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ABCBB_HUMAN (7-709): 6.22e-141: 448: 22.54
+	Hs
		252797 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ABCB7_HUMAN (1-752): 0: 608: 100.00
+	Sc
		477317 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		ATM1_YEAST (57-719): 2.33e-150: 456: 44.96
+	Hs
		437175 UBB_HUMAN (1-234): 1.14e-59: 197: 17.92		MDR1_HUMAN (7-713): 1.45e-140: 447: 21.88
+	At
		285682 UBQ9_ARATH (1-229): 8.98e-53: 182: 17.02		AB4B_ARATH (7-710): 2.37e-145: 459: 22.00
+	At
		1092195 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		AB25B_ARATH (118-713): 9.58e-153: 463: 55.81
+	At
		285677 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		AB4B_ARATH (7-710): 2.37e-145: 459: 22.00
+	At
		1092078 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		AB11B_ARATH (7-713): 6.07e-144: 456: 21.01
+	At
		1092079 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		AB12B_ARATH (7-713): 1.24e-140: 447: 21.48