HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: LRCH4 (O75427)
Leucine-rich repeat and calponin homology domain-containing protein 4 (Leucine-rich repeat neuronal protein 4) (Leucine-rich neuronal protein)
Gene: LRCH4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 683
+	Hs
		227318 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		FLII_HUMAN (139-358): 1.93e-32: 136: 19.17
+	Hs
		227427 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SCRIB_HUMAN (126-496): 3.13e-32: 136: 16.35
+	Hs
		228147 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		LRC8C_HUMAN (54-269): 1.66e-29: 127: 18.92
+	Hs
		228731 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		LRC40_HUMAN (27-263): 1.04e-28: 123: 20.71
+	Hs
		228402 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		LRRC7_HUMAN (184-545): 2.44e-17: 89: 10.93
+	Hs
		227724 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		LRCH2_HUMAN (367-574): 8.33e-10: 64.2: 6.73
+	Hs
		227528 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RSU1_HUMAN (109-246): 2.36e-10: 63.9: 34.51
+	At
		1092449 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		BRL2_ARATH (143-588): 7.58e-49: 187: 10.99
+	At
		1210483 UBQ10_ARATH (1-76): 2.29e-29: 121: 31.58		BRL2_ARATH (143-588): 7.58e-49: 187: 10.99
+	At
		1092049 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		FLS2_ARATH (1-214): 3.75e-27: 120: 20.18
+	Hs
		475933 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		LRSM1_HUMAN (45-180): 1.53e-23: 107: 29.20