HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: G3P (P04406)
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-)
Gene: GAPDH

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.709

Property	Details
Experiments	25959826, 32929329, 35509820, 35256949, 24244333
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043123 - positive regulation of canonical NF-kappaB signal transduction GO:0048471 - perinuclear region of cytoplasm and 1 others more... GO:0050821 - protein stabilization
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 335
+	Sc
		334868 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		G3P1_YEAST (4-333): 0: 538: 64.24
+	Sc
		334587 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		G3P3_YEAST (4-333): 0: 536: 64.85
+	Sc
		334410 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		G3P2_YEAST (4-333): 0: 535: 64.55
+	At
		1092081 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		G3PC2_ARATH (3-333): 0: 545: 67.27
+	Zm
		24728 A0A1D6IJX7_MAIZE (233-459): 1.19e-26: 116: 21.70		C4JBS8_MAIZE (1-335): 0: 551: 69.44
+	At
		639321 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		G3PC1_ARATH (3-333): 0: 544: 67.57
+	At
		1092156 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		G3PA2_ARATH (2-333): 7.09e-163: 462: 46.43