Protein: TM216
Transmembrane protein 216

Gene: TM216, TMEM216
Organism: Homo sapiens
Interactions: 243
UniProt ID: Q9P0N5

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005929 - cilium
GO:0016020 - membrane
GO:0035869 - ciliary transition zone

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

245749

GANP
Germinal-center associated nuclear protein

1

0

High-throughput

0.518

High

180083

BET1
BET1 homolog

1

5

High-throughput

0.479

High

192336

YKT6
Synaptobrevin homolog YKT6

1

1

High-throughput

0.479

High

226234

STX6
Syntaxin-6

1

5

High-throughput

0.479

High

249904

STX10
Syntaxin-10

1

4

High-throughput

0.479

High

296584

STAM2
Signal transducing adapter molecule 2

1

1

High-throughput

0.479

High

338556

SC24B
Protein transport protein Sec24B

1

1

High-throughput

0.479

High

338662

AGRL2
Adhesion G protein-coupled receptor L2

1

1

High-throughput

0.479

High

390791

TFR1
Transferrin receptor protein 1

1

1

High-throughput

0.479

High

607665

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

2

High-throughput

0.479

High

611395

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

2

High-throughput

0.479

High

643402

OSBP1
Oxysterol-binding protein 1

1

2

High-throughput

0.479

High

727544

SC6A6
Sodium- and chloride-dependent taurine transporter

1

3

High-throughput

0.479

High

869688

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

3

High-throughput

0.479

High

870455

SC6A9
Sodium- and chloride-dependent glycine transporter 1

1

3

High-throughput

0.479

High

895120

EMD
Emerin

1

1

High-throughput

0.479

High

904171

BAP31
B-cell receptor-associated protein 31

1

2

High-throughput

0.479

High

933492

S12A2
Solute carrier family 12 member 2

1

1

High-throughput

0.479

High

989391

VAMP2
Vesicle-associated membrane protein 2

1

2

High-throughput

0.479

High

1097909

STX5
Syntaxin-5

1

3

High-throughput

0.479

High

1125711

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

1

High-throughput

0.479

High

1139594

S39AE
Metal cation symporter ZIP14

1

3

High-throughput

0.479

High

1149039

SC23B
Protein transport protein Sec23B

1

1

High-throughput

0.479

High

1154772

VAMP3
Vesicle-associated membrane protein 3

1

1

High-throughput

0.479

High

1195397

ANO6
Anoctamin-6

1

1

High-throughput

0.479

High

1218868

GP107
Protein GPR107

1

2

High-throughput

0.479

High

1249570

TM107
Transmembrane protein 107

1

1

Small-scale

0.479

High

1288673

GPAT4
Glycerol-3-phosphate acyltransferase 4

1

3

High-throughput

0.479

High

1329359

ARFG2
ADP-ribosylation factor GTPase-activating protein 2

1

1

High-throughput

0.479

High

1333786

TM87A
Transmembrane protein 87A

1

2

High-throughput

0.479

High

1338490

PCAT1
Lysophosphatidylcholine acyltransferase 1

1

3

High-throughput

0.479

High

1340251

MSPD2
Motile sperm domain-containing protein 2

1

2

High-throughput

0.479

High

1346811

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

2

High-throughput

0.479

High

1363471

S39A7
Zinc transporter SLC39A7

1

3

High-throughput

0.479

High

1368306

STAM1
Signal transducing adapter molecule 1

1

1

High-throughput

0.479

High

1408243

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

3

High-throughput

0.479

High

1416730

OSB11
Oxysterol-binding protein-related protein 11

1

2

High-throughput

0.479

High

1419807

OSBL8
Oxysterol-binding protein-related protein 8

1

2

High-throughput

0.479

High

1431913

S38A1
Sodium-coupled neutral amino acid symporter 1

1

1

High-throughput

0.479

High

1431950

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

3

High-throughput

0.479

High

1445854

ARFG3
ADP-ribosylation factor GTPase-activating protein 3

1

1

High-throughput

0.479

High

1446628

GP108
Protein GPR108

1

2

High-throughput

0.479

High

1451051

ANO10
Anoctamin-10

1

1

High-throughput

0.479

High

1452698

BET1L
BET1-like protein

1

4

High-throughput

0.479

High

1453816

VAPA
Vesicle-associated membrane protein-associated protein A

1

2

High-throughput

0.479

High

1453926

VANG2
Vang-like protein 2

1

1

High-throughput

0.479

High

1453928

S12A4
Solute carrier family 12 member 4

1

2

High-throughput

0.479

High

124117

SNP23
Synaptosomal-associated protein 23

1

0

High-throughput

0.458

High

133591

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.458

High

160636

IRS4
Insulin receptor substrate 4

1

0

High-throughput

0.458

High

178850

SCAM1
Secretory carrier-associated membrane protein 1

1

0

High-throughput

0.458

High

181452

PGRC2
Membrane-associated progesterone receptor component 2

1

0

High-throughput

0.458

High

209129

CYB5B
Cytochrome b5 type B

1

0

High-throughput

0.458

High

215674

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.458

High

247539

FZD6
Frizzled-6

1

0

High-throughput

0.458

High

254235

CTND1
Catenin delta-1

1

0

High-throughput

0.458

High

291573

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.458

High

292762

RENR
Renin receptor

1

0

High-throughput

0.458

High

297282

PRAF3
PRA1 family protein 3

1

0

High-throughput

0.458

High

300057

CBPD
Carboxypeptidase D

1

0

High-throughput

0.458

High

331928

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.458

High

339609

ACSL3
Fatty acid CoA ligase Acsl3

1

0

High-throughput

0.458

High

423356

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.458

High

431927

ITB1
Integrin beta-1

1

0

High-throughput

0.458

High

467633

4F2
Amino acid transporter heavy chain SLC3A2

1

0

High-throughput

0.458

High

469222

SRPRA
Signal recognition particle receptor subunit alpha

1

0

High-throughput

0.458

High

548624

MPRI
Cation-independent mannose-6-phosphate receptor

1

0

High-throughput

0.458

High

596726

NCPR
NADPH--cytochrome P450 reductase

1

0

High-throughput

0.458

High

720065

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.458

High

774003

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.458

High

837882

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

847727

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

873340

COPD
Coatomer subunit delta

1

0

High-throughput

0.458

High

878348

MRP
MARCKS-related protein

1

0

High-throughput

0.458

High

878719

CAMLG
Guided entry of tail-anchored proteins factor CAMLG

1

0

High-throughput

0.458

High

880726

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

898147

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

1

0

High-throughput

0.458

High

901633

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.458

High

906206

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

0

High-throughput

0.458

High

907856

CLCN7
H(+)/Cl(-) exchange transporter 7

1

0

High-throughput

0.458

High

920660

ARFP1
Arfaptin-1

1

0

High-throughput

0.458

High

921816

COPB
Coatomer subunit beta

1

0

High-throughput

0.458

High

952476

UB2G2
Ubiquitin-conjugating enzyme E2 G2

1

0

High-throughput

0.458

High

959281

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

1010883

TMF1
TATA element modulatory factor

1

0

High-throughput

0.458

High

1031876

LAT1
Large neutral amino acids transporter small subunit 1

1

0

High-throughput

0.458

High

1041337

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

1058701

CKAP4
Cytoskeleton-associated protein 4

1

0

High-throughput

0.458

High

1061312

RHG01
Rho GTPase-activating protein 1

1

0

High-throughput

0.458

High

1063081

S20A2
Sodium-dependent phosphate transporter 2

1

0

High-throughput

0.458

High

1063196

GOGA3
Golgin subfamily A member 3

1

0

High-throughput

0.458

High

1103669

PHLP
Phosducin-like protein

1

0

High-throughput

0.458

High

1129898

EPN4
Clathrin interactor 1

1

0

High-throughput

0.458

High

1131848

LBR
Delta(14)-sterol reductase LBR

1

0

High-throughput

0.458

High

1153353

AAAT
Neutral amino acid transporter B(0)

1

0

High-throughput

0.458

High

1155278

VAS1
V-type proton ATPase subunit S1

1

0

High-throughput

0.458

High

1164275

VATF
V-type proton ATPase subunit F

1

0

High-throughput

0.458

High

1201665

SFT2C
Vesicle transport protein SFT2C

1

0

High-throughput

0.458

High

1214428

GORAB
RAB6-interacting golgin

1

0

High-throughput

0.458

High

1218492

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

0

High-throughput

0.458

High

1238703

TM214
Transmembrane protein 214

1

0

High-throughput

0.458

High

1288809

KTN1
Kinectin

1

0

High-throughput

0.458

High

1294021

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

0

High-throughput

0.458

High

1309909

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.458

High

1316123

K319L
Dyslexia-associated protein KIAA0319-like protein

1

0

High-throughput

0.458

High

1316312

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

0

High-throughput

0.458

High

1326933

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.458

High

1327990

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

High-throughput

0.458

High

1330424

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

1337703

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.458

High

1339210

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

1348349

GOGA5
Golgin subfamily A member 5

1

0

High-throughput

0.458

High

1349859

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

0

High-throughput

0.458

High

1358388

SCFD1
Sec1 family domain-containing protein 1

1

0

High-throughput

0.458

High

1365073

UBXN4
UBX domain-containing protein 4

1

0

High-throughput

0.458

High

1366790

NECT2
Nectin-2

1

0

High-throughput

0.458

High

1371979

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

0

High-throughput

0.458

High

1382228

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.458

High

1382465

SYAP1
Synapse-associated protein 1

1

0

High-throughput

0.458

High

1383129

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1391311

CERS2
Ceramide synthase 2

1

0

High-throughput

0.458

High

1391667

VMP1
Vacuole membrane protein 1

1

0

High-throughput

0.458

High

1395973

DNJC1
DnaJ homolog subfamily C member 1

1

0

High-throughput

0.458

High

1399180

VMA22
Vacuolar ATPase assembly protein VMA22

1

0

High-throughput

0.458

High

1402392

CLCC1
Chloride channel CLIC-like protein 1

1

0

High-throughput

0.458

High

1402834

TM209
Transmembrane protein 209

1

0

High-throughput

0.458

High

1405095

VAT1
Synaptic vesicle membrane protein VAT-1 homolog

1

0

High-throughput

0.458

High

1405958

CDCA3
Cell division cycle-associated protein 3

1

0

High-throughput

0.458

High

1406196

PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

1

0

High-throughput

0.458

High

1412706

ESYT1
Extended synaptotagmin-1

1

0

High-throughput

0.458

High

1413789

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.458

High

1419928

WDR11
WD repeat-containing protein 11

1

0

High-throughput

0.458

High

1421167

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.458

High

1429580

LSG1
Large subunit GTPase 1 homolog

1

0

High-throughput

0.458

High

1431732

SEM6A
Semaphorin-6A

1

0

High-throughput

0.458

High

1432813

GCP60
Golgi resident protein GCP60

1

0

High-throughput

0.458

High

1435219

ALG9
Alpha-1,2-mannosyltransferase ALG9

1

0

High-throughput

0.458

High

1436708

GORS2
Golgi reassembly-stacking protein 2

1

0

High-throughput

0.458

High

1438378

VEZA
Vezatin

1

0

High-throughput

0.458

High

1438700

SENP2
Sentrin-specific protease 2

1

0

High-throughput

0.458

High

1439036

GBA2
Non-lysosomal glucosylceramidase

1

0

High-throughput

0.458

High

1439469

SEC12
Guanine nucleotide-exchange factor SEC12

1

0

High-throughput

0.458

High

1439572

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

0

High-throughput

0.458

High

1445738

WDR6
tRNA

1

0

High-throughput

0.458

High

1446115

EMC7
Endoplasmic reticulum membrane protein complex subunit 7

1

0

High-throughput

0.458

High

1451122

TMM51
Transmembrane protein 51

1

0

High-throughput

0.458

High

1453353

E2AK3
Eukaryotic translation initiation factor 2-alpha kinase 3

1

0

High-throughput

0.458

High

1453740

EMC3
ER membrane protein complex subunit 3

1

0

High-throughput

0.458

High

1453922

SEC63
Translocation protein SEC63 homolog

1

0

High-throughput

0.458

High

1453923

LCAP
Leucyl-cystinyl aminopeptidase

1

0

High-throughput

0.458

High

1453924

PALD
Paladin

1

0

High-throughput

0.458

High

1453930

MAN1
Inner nuclear membrane protein Man1

1

0

High-throughput

0.458

High

1453932

DHRS7
Dehydrogenase/reductase SDR family member 7

1

0

High-throughput

0.458

High

1453933

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.458

High

1453934

SRPRB
Signal recognition particle receptor subunit beta

1

0

High-throughput

0.458

High

1453935

UBIA1
UbiA prenyltransferase domain-containing protein 1

1

0

High-throughput

0.458

High

1453937

COPG1
Coatomer subunit gamma-1

1

0

High-throughput

0.458

High

1453938

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

0

High-throughput

0.458

High

1453939

TX264
Testis-expressed protein 264

1

0

High-throughput

0.458

High

1453940

S4A7
Sodium bicarbonate cotransporter 3

1

0

High-throughput

0.458

High

1453941

S23IP
SEC23-interacting protein

1

0

High-throughput

0.458

High

189887

STX7
Syntaxin-7

1

2

High-throughput

0.437

High

280361

SC22B
Vesicle-trafficking protein SEC22b

1

1

High-throughput

0.437

High

333242

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

2

High-throughput

0.437

High

571167

CD99
CD99 antigen

1

1

High-throughput

0.437

High

710532

EPHA2
Ephrin type-A receptor 2

1

1

High-throughput

0.437

High

914495

EFNB2
Ephrin-B2

1

1

High-throughput

0.437

High

1004221

CXAR
Coxsackievirus and adenovirus receptor

1

1

High-throughput

0.437

High

1022979

EFNB1
Ephrin-B1

1

1

High-throughput

0.437

High

1037051

DSC2
Desmocollin-2

1

1

High-throughput

0.437

High

1105254

S39A6
Zinc transporter ZIP6

1

3

High-throughput

0.437

High

1120834

DSG2
Desmoglein-2

1

1

High-throughput

0.437

High

1147452

EPHA7
Ephrin type-A receptor 7

1

1

High-throughput

0.437

High

1159879

OCLN
Occludin

1

1

High-throughput

0.437

High

1198409

GPAT3
Glycerol-3-phosphate acyltransferase 3

1

3

High-throughput

0.437

High

1205048

RABL3
Rab-like protein 3

1

1

High-throughput

0.437

High

1239559

ZNT6
Zinc transporter 6

1

2

High-throughput

0.437

High

1294849

STX12
Syntaxin-12

1

2

High-throughput

0.437

High

1322219

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

1

High-throughput

0.437

High

1326783

MALD2
MARVEL domain-containing protein 2

1

1

High-throughput

0.437

High

1346656

VANG1
Vang-like protein 1

1

1

High-throughput

0.437

High

1356117

SCRB1
Scavenger receptor class B member 1

1

2

High-throughput

0.437

High

1400732

S38A2
Sodium-coupled neutral amino acid symporter 2

1

1

High-throughput

0.437

High

1415197

TM109
Voltage-gated monoatomic cation channel TMEM109

1

1

High-throughput

0.437

High

1431088

TMX4
Thioredoxin-related transmembrane protein 4

1

1

High-throughput

0.437

High

1432769

TMX1
Thioredoxin-related transmembrane protein 1

1

1

High-throughput

0.437

High

1453920

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

1

High-throughput

0.437

High

1453925

S39AA
Zinc transporter ZIP10

1

3

High-throughput

0.437

High

1453927

STX8
Syntaxin-8

1

4

High-throughput

0.437

High

1453931

UB2J1
Ubiquitin-conjugating enzyme E2 J1

1

1

High-throughput

0.437

High

1453936

JAM1
Junctional adhesion molecule A

1

1

High-throughput

0.437

High

127196

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.249

Low

140013

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

184237

RER1
Protein RER1

1

0

High-throughput

0.249

Low

258347

TRI13
E3 ubiquitin-protein ligase TRIM13

1

0

High-throughput

0.249

Low

321056

SUN1
SUN domain-containing protein 1

1

0

High-throughput

0.249

Low

337832

SGPL1
Sphingosine-1-phosphate lyase 1

1

0

High-throughput

0.249

Low

506678

GPHRB
Golgi pH regulator B

1

0

High-throughput

0.249

Low

835017

S19A1
Reduced folate transporter

1

0

High-throughput

0.249

Low

845835

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.249

Low

956117

SPCS3
Signal peptidase complex subunit 3

1

0

High-throughput

0.249

Low

994965

SC11A
Signal peptidase complex catalytic subunit SEC11A

1

0

High-throughput

0.249

Low

1034364

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

0

High-throughput

0.249

Low

1089167

TM115
Transmembrane protein 115

1

0

High-throughput

0.249

Low

1111735

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.249

Low

1136183

SPCS2
Signal peptidase complex subunit 2

1

0

High-throughput

0.249

Low

1136399

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.249

Low

1150414

NCOA2
Nuclear receptor coactivator 2

1

0

High-throughput

0.249

Low

1152887

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.249

Low

1164361

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

1

0

High-throughput

0.249

Low

1191806

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

1

0

High-throughput

0.249

Low

1206914

TOIP1
Torsin-1A-interacting protein 1

1

0

High-throughput

0.249

Low

1225924

STEA3
Metalloreductase STEAP3

1

0

High-throughput

0.249

Low

1225979

F91A1
Protein FAM91A1

1

0

High-throughput

0.249

Low

1238199

RHBD2
Rhomboid domain-containing protein 2

1

0

High-throughput

0.249

Low

1243251

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

0

High-throughput

0.249

Low

1276401

LYSM3
LysM and putative peptidoglycan-binding domain-containing protein 3

1

0

High-throughput

0.249

Low

1288280

LYRIC
Protein LYRIC

1

0

High-throughput

0.249

Low

1293303

LSR
Lipolysis-stimulated lipoprotein receptor

1

0

High-throughput

0.249

Low

1294515

VRK2
Serine/threonine-protein kinase VRK2

1

0

High-throughput

0.249

Low

1308010

RELL1
RELT-like protein 1

1

0

High-throughput

0.249

Low

1308231

PLD3
5'-3' exonuclease PLD3

1

0

High-throughput

0.249

Low

1314641

M21D2
Nucleotidyltransferase MB21D2

1

0

High-throughput

0.249

Low

1316523

UNC5B
Netrin receptor UNC5B

1

0

High-throughput

0.249

Low

1327064

VMA12
Vacuolar ATPase assembly protein VMA12

1

0

High-throughput

0.249

Low

1327738

MACOI
Macoilin

1

0

High-throughput

0.249

Low

1328218

JAGN1
Protein jagunal homolog 1

1

0

High-throughput

0.249

Low

1350299

C99L2
CD99 antigen-like protein 2

1

0

High-throughput

0.249

Low

1357340

THEM6
Protein THEM6

1

0

High-throughput

0.249

Low

1393778

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1406243

CHP1
Calcineurin B homologous protein 1

1

0

High-throughput

0.249

Low

1433279

IFG15
Torsin-1A-interacting protein 2, isoform IFRG15

1

0

High-throughput

0.249

Low

1435044

RETR1
Reticulophagy regulator 1

1

0

High-throughput

0.249

Low

1437518

WDR41
WD repeat-containing protein 41

1

0

High-throughput

0.249

Low

1439716

JPH1
Junctophilin-1

1

0

High-throughput

0.249

Low

1446934

RTN4
Reticulon-4

1

0

High-throughput

0.249

Low

1447601

ITM2C
Integral membrane protein 2C

1

0

High-throughput

0.249

Low

1449688

TB22B
TBC1 domain family member 22B

1

0

High-throughput

0.249

Low

1451092

BSDC1
BSD domain-containing protein 1

1

0

High-throughput

0.249

Low

1451969

NSMA3
Sphingomyelin phosphodiesterase 4

1

0

High-throughput

0.249

Low

1452964

USE1
Vesicle transport protein USE1

1

0

High-throughput

0.249

Low

1453921

STX18
Syntaxin-18

1

0

High-throughput

0.249

Low

1453929

JAG2
Protein jagged-2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025