HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: RS25 (P62851)
Small ribosomal subunit protein eS25 (40S ribosomal protein S25)
Gene: RPS25

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.709

Property	Details
Experiments	25959826, 32929329, 35509820, 35256949, 24244333
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0014069 - postsynaptic density
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 125
+	Hs
		312555 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		RS25_HUMAN (1-125): 3.79e-46: 147: 100.00
+	Hs
		475588 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		RS25_HUMAN (1-125): 3.79e-46: 147: 100.00
+	At
		1092333 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		RS252_ARATH (1-113): 7.48e-39: 128: 53.98
+	At
		1092422 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		RS254_ARATH (1-113): 3.57e-38: 126: 53.10