HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: CSTFT (Q9H0L4)
Cleavage stimulation factor subunit 2 tau variant (CF-1 64 kDa subunit tau variant) (Cleavage stimulation factor 64 kDa subunit tau variant) (CSTF 64 kDa subunit tau variant) (TauCstF-64)
Gene: CSTF2T

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35987950
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 616
+	Hs
		226655 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CSTF2_HUMAN (1-615): 8.49e-64: 222: 67.81
+	Hs
		227414 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CIRBP_HUMAN (11-108): 3.2e-35: 132: 30.61
+	Hs
		227354 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP4_HUMAN (9-201): 1.63e-27: 119: 15.90
+	Hs
		226375 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP1_HUMAN (7-554): 3.29e-25: 112: 10.80
+	Hs
		228678 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP3_HUMAN (7-201): 4.69e-24: 108: 14.72
+	Hs
		228318 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP5_HUMAN (20-193): 1.42e-24: 107: 17.61
+	Hs
		227642 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PAP1L_HUMAN (7-215): 6.06e-20: 95.9: 14.83
+	Hs
		1031383 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		PABP4_HUMAN (9-201): 1.63e-27: 119: 15.90
+	Hs
		312602 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		CIRBP_HUMAN (11-108): 3.2e-35: 132: 30.61
+	Hs
		312462 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		PABP1_HUMAN (7-554): 3.29e-25: 112: 10.80
+	Hs
		475739 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		CIRBP_HUMAN (11-108): 3.2e-35: 132: 30.61
+	At
		975638 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		RBG8_ARATH (19-93): 1.34e-33: 128: 33.33
+	Hs
		475631 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		RBM3_HUMAN (17-94): 1.52e-32: 124: 38.46
+	Hs
		475708 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP4_HUMAN (9-201): 1.63e-27: 119: 15.90
+	Hs
		475288 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP1_HUMAN (7-554): 3.29e-25: 112: 10.80
+	At
		981214 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		CP31A_ARATH (17-110): 3.15e-25: 108: 27.66
+	At
		186465 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		PABP4_ARATH (16-187): 1.29e-20: 98.2: 20.00
+	At
		983451 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		PABP5_ARATH (13-201): 5.59e-19: 93.2: 17.71