HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: SMRCD (Q9H4L7)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12) (ATP-dependent helicase 1) (hHEL1)
Gene: SMARCAD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0043130 - ubiquitin binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 1026
+	Hs
		226905 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SMCA2_HUMAN (55-1024): 0: 689: 25.05
+	Hs
		225984 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SMCA5_HUMAN (353-1021): 0: 594: 29.60
+	Hs
		312519 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		SMCA4_HUMAN (96-1024): 0: 693: 26.54
+	Hs
		475678 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		CHD3_HUMAN (338-1022): 0: 621: 27.64
+	Hs
		228826 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		HELLS_HUMAN (479-999): 1.2e-93: 318: 37.59
+	Hs
		475648 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ERCC6_HUMAN (21-1021): 0: 595: 20.53