Protein: RRP9
Ribosomal RNA-processing protein 9

Gene: RRP9
Organism: Saccharomyces cerevisiae S288C
Interactions: 117
UniProt ID: Q06506

Gene Ontology (top 5):
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

678467

PWP2
Periodic tryptophan protein 2

6

20

High-throughput

0.945

High

1046042

DHR1
Probable ATP-dependent RNA helicase DHR1

6

20

Small-scale

0.943

High

1055434

UTP4
U3 small nucleolar RNA-associated protein 4

4

19

Small-scale

0.895

High

1039858

UTP17
NET1-associated nuclear protein 1

3

18

High-throughput

0.861

High

1046258

UTP15
U3 small nucleolar RNA-associated protein 15

3

19

High-throughput

0.861

High

1053114

UTP13
U3 small nucleolar RNA-associated protein 13

3

20

High-throughput

0.861

High

754340

DCA13
Protein SOF1

2

17

High-throughput

0.754

High

1055454

NOP58
Nucleolar protein 58

7

11

Small-scale

0.741

High

817639

UTP7
U3 small nucleolar RNA-associated protein 7

2

19

High-throughput

0.737

High

844624

UTP10
U3 small nucleolar RNA-associated protein 10

6

5

Small-scale

0.731

High

677577

KRR1
KRR1 small subunit processome component

5

1

High-throughput

0.716

High

865179

MPP10
U3 small nucleolar RNA-associated protein MPP10

5

7

Small-scale

0.716

High

1050172

RRP5
rRNA biogenesis protein RRP5

5

20

Small-scale

0.715

High

1055432

NOC4
Nucleolar complex protein 4

5

7

Small-scale

0.714

High

763631

UTP20
U3 small nucleolar RNA-associated protein 20

6

0

Small-scale

0.703

High

918832

UTP22
U3 small nucleolar RNA-associated protein 22

4

2

High-throughput

0.701

High

1053783

SGD1
Suppressor of glycerol defect protein 1

4

11

Small-scale

0.701

High

779164

DHR2
Probable ATP-dependent RNA helicase DHR2

1

13

High-throughput

0.698

High

924193

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

20

High-throughput

0.698

High

798321

ENP1
Essential nuclear protein 1

5

3

Small-scale

0.695

High

924640

NAT10
RNA cytidine acetyltransferase

4

3

High-throughput

0.694

High

1055443

BMS1
Ribosome biogenesis protein BMS1

4

9

High-throughput

0.694

High

1055442

UTP16
U3 small nucleolar RNA-associated protein 16

5

0

High-throughput

0.686

High

925203

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

3

2

High-throughput

0.667

High

1036416

UTP6
U3 small nucleolar RNA-associated protein 6

3

4

High-throughput

0.667

High

1055452

NOP56
Nucleolar protein 56

3

11

High-throughput

0.667

High

1055437

RCL1
rRNA processing protein RCL1

3

2

High-throughput

0.656

High

1055457

NOP14
Nucleolar complex protein 14

3

2

High-throughput

0.656

High

585385

FBRL
rRNA 2'-O-methyltransferase fibrillarin

3

7

Small-scale

0.642

High

1055453

RRP36
rRNA biogenesis protein RRP36

3

0

Small-scale

0.639

High

806580

UTP9
U3 small nucleolar RNA-associated protein 9

3

0

High-throughput

0.638

High

436185

RS13
Small ribosomal subunit protein uS15

2

5

High-throughput

0.628

High

688948

RS5
Small ribosomal subunit protein uS7

2

7

High-throughput

0.628

High

1030580

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

15

High-throughput

0.618

High

823392

UTP18
U3 small nucleolar RNA-associated protein 18

1

3

High-throughput

0.618

High

852610

ROK1
ATP-dependent RNA helicase ROK1

1

17

High-throughput

0.618

High

864525

MTR4
ATP-dependent RNA helicase DOB1

1

20

High-throughput

0.618

High

919006

PESC
Pescadillo homolog

1

3

High-throughput

0.618

High

1043291

HAS1
ATP-dependent RNA helicase HAS1

1

20

High-throughput

0.618

High

1055431

RRP9
Ribosomal RNA-processing protein 9

1

18

High-throughput

0.618

High

1055451

DBP10
ATP-dependent RNA helicase DBP10

1

20

High-throughput

0.618

High

836203

DIM1
Dimethyladenosine transferase

2

4

High-throughput

0.611

High

627871

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

1

20

High-throughput

0.595

High

825566

UTP25
U3 small nucleolar RNA-associated protein 25

2

0

Small-scale

0.585

High

826216

FAF1
Protein FAF1

2

0

Small-scale

0.585

High

512159

RS4A
Small ribosomal subunit protein eS4A

2

5

High-throughput

0.584

High

923988

CSL4
Exosome complex component CSL4

2

3

High-throughput

0.584

High

1046798

UTP14
U3 small nucleolar RNA-associated protein 14

2

12

High-throughput

0.584

High

1053517

UTP21
U3 small nucleolar RNA-associated protein 21

2

18

Small-scale

0.584

High

1055447

RRP6
Exosome complex exonuclease RRP6

2

6

High-throughput

0.584

High

1055439

AVO1
Target of rapamycin complex 2 subunit AVO1

1

0

High-throughput

0.578

High

671159

SIS1
Protein SIS1

2

16

High-throughput

0.571

High

673236

RRP7
Ribosomal RNA-processing protein 7

2

0

High-throughput

0.559

High

546400

SSB1
Ribosome-associated molecular chaperone SSB1

2

15

High-throughput

0.504

High

733621

PROB
Glutamate 5-kinase

1

2

High-throughput

0.489

High

735180

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

747051

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

6

High-throughput

0.479

High

782109

RL1D1
Ribosome biogenesis protein UTP30

1

6

High-throughput

0.479

High

804754

RRP4
Exosome complex component RRP4

1

11

High-throughput

0.479

High

808314

RRP8
25S rRNA

1

1

High-throughput

0.479

High

818350

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

2

High-throughput

0.479

High

863140

RRP41
Exosome complex component SKI6

1

19

High-throughput

0.479

High

864967

NOP9
Nucleolar protein 9

1

2

Small-scale

0.479

High

871062

NOL10
Ribosome biogenesis protein ENP2

1

4

High-throughput

0.479

High

918898

RRP46
Exosome complex component RRP46

1

14

High-throughput

0.479

High

923258

ESF2
Pre-rRNA-processing protein ESF2

1

1

High-throughput

0.479

High

924852

NOP15
Ribosome biogenesis protein 15

1

20

High-throughput

0.479

High

932235

ORC1
Origin recognition complex subunit 1

1

10

High-throughput

0.479

High

1042244

TOM1
E3 ubiquitin-protein ligase TOM1

1

10

High-throughput

0.479

High

1045110

UTP5
U3 small nucleolar RNA-associated protein 5

1

17

High-throughput

0.479

High

1051164

FCF1
rRNA-processing protein FCF1

1

1

High-throughput

0.479

High

1051712

RRP45
Exosome complex component RRP45

1

12

High-throughput

0.479

High

1054541

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

3

High-throughput

0.479

High

1055433

BFR2
Protein BFR2

1

3

High-throughput

0.479

High

1055438

RRP44
Exosome complex exonuclease DIS3

1

10

High-throughput

0.479

High

1055440

RRP40
Exosome complex component RRP40

1

4

High-throughput

0.479

High

1055444

FCF2
rRNA-processing protein FCF2

1

1

High-throughput

0.479

High

1055445

SAS10
Something about silencing protein 10

1

1

High-throughput

0.479

High

1055448

MAK21
Ribosome biogenesis protein MAK21

1

7

High-throughput

0.479

High

1055449

UTP12
U3 small nucleolar RNA-associated protein 12

1

19

High-throughput

0.479

High

1055450

RRP42
Exosome complex component RRP42

1

12

High-throughput

0.479

High

1055455

RRP12
Ribosomal RNA-processing protein 12

1

3

High-throughput

0.479

High

672956

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

758413

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

804962

LRP1
Exosome complex protein LRP1

1

0

High-throughput

0.458

High

825087

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

871129

MTR3
Exosome complex component MTR3

1

0

High-throughput

0.458

High

919178

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

High-throughput

0.458

High

1054895

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.458

High

1055436

CMS1
Protein CMS1

1

0

High-throughput

0.458

High

1055458

PNO1
Pre-rRNA-processing protein PNO1

1

0

High-throughput

0.458

High

509729

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

17

High-throughput

0.457

High

359534

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

6

High-throughput

0.457

High

416482

HXKA
Hexokinase-1

1

4

High-throughput

0.457

High

590731

HSP26
Heat shock protein 26

1

3

High-throughput

0.457

High

503256

RS22A
Small ribosomal subunit protein uS8A

1

3

High-throughput

0.437

High

708271

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

709999

BMH1
Protein BMH1

1

10

High-throughput

0.437

High

748062

SMY2
Protein SMY2

1

1

High-throughput

0.437

High

812682

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

826862

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.437

High

1055435

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

1055446

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.437

High

1055456

RS22B
Small ribosomal subunit protein uS8B

1

3

High-throughput

0.437

High

525255

HSP71
Heat shock protein SSA1

1

14

High-throughput

0.407

High

527765

HSP72
Heat shock protein SSA2

1

16

High-throughput

0.407

High

531901

RL4A
Large ribosomal subunit protein uL4A

1

6

High-throughput

0.407

High

819884

SSB2
Ribosome-associated molecular chaperone SSB2

1

15

High-throughput

0.407

High

836911

MPG1
Mannose-1-phosphate guanyltransferase

1

6

High-throughput

0.407

High

917345

RRT6
Regulator of rDNA transcription protein 6

1

0

High-throughput

0.279

Low

806701

AIM46
Altered inheritance of mitochondria protein 46, mitochondrial

1

0

High-throughput

0.261

Low

803780

PIH1
Protein interacting with Hsp90 1

1

0

Small-scale

0.251

Low

558874

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

805268

SBE22
Protein SBE22

1

0

High-throughput

0.249

Low

1055441

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

1051544

NSE3
Non-structural maintenance of chromosome element 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025