HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: BCLF1 (Q9NYF8)
Bcl-2-associated transcription factor 1 (Btf) (BCLAF1 and THRAP3 family member 1)
Gene: BCLAF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32929329, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016607 - nuclear speck GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 920
+	Hs
		229118 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TR150_HUMAN (46-920): 4.85e-76: 269: 33.00
+	Hs
		227370 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		MYO9B_HUMAN (101-542): 1.34e-18: 93.8: 9.91
+	Hs
		229228 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PCLO_HUMAN (96-875): 9.08e-13: 75: 10.41
+	Hs
		228210 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TITIN_HUMAN (94-778): 5.89e-11: 69.2: 8.45
+	Hs
		228373 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CHAP1_HUMAN (114-643): 1.32e-09: 64.2: 11.09
+	Hs
		475943 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		OTOG_HUMAN (101-603): 1.8e-21: 103: 9.33
+	At
		1092118 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		Q9LIE8_ARATH (148-700): 7.88e-09: 61.9: 6.13