HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: DJB11 (Q9UBS4)
DnaJ homolog subfamily B member 11 (APOBEC1-binding protein 2) (ABBP-2) (DnaJ protein homolog 9) (ER-associated DNAJ) (ER-associated Hsp40 co-chaperone) (Endoplasmic reticulum DNA J domain-containing protein 3) (ER-resident protein ERdj3) (ERdj3) (ERj3p) (HEDJ) (Human DnaJ protein 9) (hDj-9) (PWP1-interacting protein 4)
Gene: DNAJB11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005783 - endoplasmic reticulum
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 358
+	Hs
		226636 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DNJA1_HUMAN (20-356): 3.06e-116: 344: 31.88
+	Hs
		228971 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DNJB4_HUMAN (23-346): 1.28e-115: 340: 30.29
+	Hs
		226020 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DNJA2_HUMAN (21-349): 3.9e-113: 336: 34.35
+	Hs
		228188 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DNJA4_HUMAN (20-356): 5.88e-113: 335: 32.43
+	Hs
		226562 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DNJB1_HUMAN (23-344): 5.46e-108: 321: 30.41
+	Sc
		477153 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		MAS5_YEAST (20-355): 2.54e-108: 324: 32.97
+	Hs
		475389 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		DNJA1_HUMAN (20-356): 3.06e-116: 344: 31.88
+	Hs
		243272 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		DNJA2_HUMAN (21-349): 3.9e-113: 336: 34.35
+	Hs
		476114 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		DNJA4_HUMAN (20-356): 5.88e-113: 335: 32.43
+	Hs
		475355 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		DNJB1_HUMAN (23-344): 5.46e-108: 321: 30.41
+	At
		1012787 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		Q0WN54_ARATH (25-350): 3.33e-106: 322: 30.33
+	At
		1091924 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		DNAJ3_ARATH (26-353): 8.42e-105: 316: 34.54
+	At
		67521 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		A8MR40_ARATH (23-343): 5.6e-38: 139: 32.11