Interactor 1: SAHH2 (O43865)
S-adenosylhomocysteine hydrolase-like protein 1 (DC-expressed AHCY-like molecule) (IP(3)Rs binding protein released with IP(3)) (IRBIT) (Putative adenosylhomocysteinase 2) (S-adenosyl-L-homocysteine hydrolase 2) (AdoHcyase 2)
Gene: AHCYL1

Interactor 2: SAHH2 (O43865)
S-adenosylhomocysteine hydrolase-like protein 1 (DC-expressed AHCY-like molecule) (IP(3)Rs binding protein released with IP(3)) (IRBIT) (Putative adenosylhomocysteinase 2) (S-adenosyl-L-homocysteine hydrolase 2) (AdoHcyase 2)
Gene: AHCYL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.896

The method score is based on:

Property Details
Experiments 25416956, 32296183, 31839598, unassigned1304
Identification Methods two hybrid, cross-linking study, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AdoHcyase~AdoHcyase, AdoHcyase~AdoHcyase_NAD, AdoHcyase_NAD~AdoHcyase_NAD
Common GO terms GO:0003723 - RNA binding
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0006611 - protein export from nucleus
and 15 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 530
Hs

1 530
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Hs
+ Dm
+ Zm
+ Ph

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Last updated: 11Aug2025