Interactor 1: PHLP1 (O60346)
PH domain leucine-rich repeat-containing protein phosphatase 1 (EC 3.1.3.16) (Pleckstrin homology domain-containing family E member 1) (PH domain-containing family E member 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP)
Gene: PHLPP1

Interactor 2: UBP46 (P62068)
Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.4.19.12) (Deubiquitinating enzyme 46) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46)
Gene: USP46

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.754

The method score is based on:

Property Details
Experiments 22391563, 26186194, 28514442, 33029497, 33961781, 19615732, 27880917, 24145035
Identification Methods enzymatic study, affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0046872 - metal ion binding
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1717
Hs

1 366
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024